| Gene Symbol |
NUBP2
|
| Entrez Gene |
10101
|
| Alt Symbol |
CFD1, NBP 2, NUBP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nucleotide binding protein 2
|
| Other Description |
cytosolic Fe-S cluster assembly factor NUBP2|homolog of yeast cytosolic Fe-S cluster deficient 1|nucleotide binding protein 2 (MinD homolog, E. coli)
|
| Swissprots |
Q9NWB2 D3DU80 Q9Y5Y2
|
| Accessions |
CAC36077 EAW85613 EAW85614 EAW85615 EAW85616 EAW85617 Q9Y5Y2 AF118394 AAD45242 AK001023 BAA91471 AK093593 AK124460 AK300696 BAH13326 AK315611 BAG37980 BC002768 AAH02768 BC008005 AAH08005 BF439443 BI196883 BU189242 BU680530 BX446436 BX648907 Z36821 XM_005255027 XP_005255084 XM_005255028 XP_005255085 XM_005255030 XP_005255087 XM_011522338 XP_011520640 NM_001284501 NP_001271430 NM_001284502 NP_001271431 NM_012225 NP_036357 NR_104318
|
| Function |
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. {ECO:0000255|HAMAP-Rule:MF_03039}.
|
| Subcellular Location |
Nucleus {ECO:0000255|HAMAP-Rule:MF_03039}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000255|HAMAP-Rule:MF_03039}. Note=Enriched at the centrosomes during mitosis. {ECO:0000255|HAMAP-Rule:MF_03039}.
|
| Tissue Specificity |
Widely expressed with highest expression in skeletal muscle.
|
![Western Blot: NUBP2 Overexpression Lysate (Adult Normal) [NBL1-13846] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for NUBP2.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/5445_NUBP2%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-13846-img0002.jpg)