Gene Symbol | CAMK2N2 |
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Entrez Gene | 94032 |
Alt Symbol | CAM-KIIN, CAMKIIN |
Species | Human |
Gene Type | protein-coding |
Description | calcium/calmodulin-dependent protein kinase II inhibitor 2 |
Other Description | CaM-KII inhibitory protein |
Swissprots | Q96S95 |
Accessions | EAW78280 EAW78281 Q96S95 AY037149 AAK67630 BC105077 AAI05078 BC105079 AAI05080 NM_033259 NP_150284 |
Function | Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2. {ECO:0000269|PubMed:11444830}. |
Subcellular Location | Nucleus. Cytoplasm, cytosol. Note=Excluded from nucleus when coexpressed with activated CAMK2. {ECO:0000250}. |
Tissue Specificity | Expressed in cell lines including hemopoietic cell lines and some tumor cell lines. Highly Expressed in stimulated dendritic cell (DC) and weakly expressed in unstimulated mature and immature DC. Highly expressed in kidney, liver, in cell lines HeLaS3, lymphoblastic leukemia MOLT-4, and Burkitt's lymphoma Raji. Moderately expressed in heart, skeletal muscle, placenta, and chronic myelogenous leukemia K-562 cells. Weakly expressed in small intestine, colorectal adenocarcinoma SW480, and lung carcinoma A-549 cells. {ECO:0000269|PubMed:11444830}. |
Human CAMKCN2 full length protein - ab183229 from Abcam
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CAMK2N2 / CAMKIIN Blocking Peptide - LS-E789 from LifeSpan Bioscience
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CAMK2N2 / CAMKIIN Blocking Peptide - LS-E26789 from LifeSpan Bioscience
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CAMK2N2-Antibody-N-term-Blocking-peptide - BP11140a from Abgent, a WuXi AppTec company
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CAMKIIN blocking peptide - GTX88666-PEP from GeneTex
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CAMK2N2 protein (His tag) - 80R-3909 from Fitzgerald
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CAMKCN2 Peptide - AC21-1620-P from Abcore
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CAMK2N2 (1-79, His-tag) - AR51596PU-N from Acris Antibodies
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CAMK2N2 (1-79, His-tag) - AR51596PU-S from Acris Antibodies
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CAM Kinase Inhibitor 2 Peptide - 46-821P from ProSci
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Recombinant Human Calcium/calmodulin-dependent protein kinase II inhibitor 2(CAM - CSB-YP004470HU CSB-EP004470HU CSB-BP004470HU CSB-MP004470HU from Cusabio
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CAMK2N2, 1-79aa, Human, His tag, E.coli - ATGP2776 from ATGen
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CAMK2N2 - TP311256 from Acris Antibodies
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Calcium/calmodulin-dependent protein kinase II inhibitor 2 (CAMK2N2), Recombinant Protein - MBS1383224 from MyBioSource
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CAMK2N2, Recombinant Protein - MBS205921 from MyBioSource
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CAMKIIN, Peptide - MBS425154 from MyBioSource
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CAMK2N2 Peptide, Human - M34GP02321H from Creative Peptides
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CaMKIIN2 Recombinant Protein - NBP2-51788 from Novus Biologicals
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CAMK2N2 - PAT-82775-1 from Nordic BioSite
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CAMK2N2 - PAT-82775-2 from Nordic BioSite
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CAMK2N2 fusion protein - Ag26872 from Proteintech Group
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CaMKIIN2 Recombinant Protein Antigen - NBP2-58609PEP from Novus Biologicals
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