| Gene Symbol |
NMUR2
|
| Entrez Gene |
56923
|
| Alt Symbol |
FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
neuromedin U receptor 2
|
| Other Description |
G-protein coupled receptor FM-4|G-protein coupled receptor TGR-1|growth hormone secretagogue receptor family, member 4|neuromedin-U receptor 2
|
| Swissprots |
Q96AM5 Q9GZQ4 Q7LC54 Q9NRA6
|
| Accessions |
EAW61653 Q9GZQ4 AB041228 BAB13721 AF242874 AAF82755 AF272363 AAG24794 AF292402 AAG03064 AI023570 BC016938 AAH16938 BC067776 AAH67776 DQ891777 ABM82703 DQ894961 ABM85887 XM_011537669 XP_011535971 XM_011537670 XP_011535972 NM_020167 NP_064552
|
| Function |
Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus. {ECO:0000269|PubMed:10887190, ECO:0000269|PubMed:10894543, ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:11010960}.
|
| Top Pathways |
Neuroactive ligand-receptor interaction
|