Gene Symbol | NMUR2 |
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Entrez Gene | 56923 |
Alt Symbol | FM-4, FM4, NMU-R2, NMU2R, TGR-1, TGR1 |
Species | Human |
Gene Type | protein-coding |
Description | neuromedin U receptor 2 |
Other Description | G-protein coupled receptor FM-4|G-protein coupled receptor TGR-1|growth hormone secretagogue receptor family, member 4|neuromedin-U receptor 2 |
Swissprots | Q96AM5 Q9GZQ4 Q7LC54 Q9NRA6 |
Accessions | EAW61653 Q9GZQ4 AB041228 BAB13721 AF242874 AAF82755 AF272363 AAG24794 AF292402 AAG03064 AI023570 BC016938 AAH16938 BC067776 AAH67776 DQ891777 ABM82703 DQ894961 ABM85887 XM_011537669 XP_011535971 XM_011537670 XP_011535972 NM_020167 NP_064552 |
Function | Receptor for the neuromedin-U and neuromedin-S neuropeptides. {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Predominantly expressed in the CNS, particularly in the medulla oblongata, pontine reticular formation, spinal cord, and thalamus. High level in testis whereas lower levels are present in a variety of peripheral tissues including the gastrointestinal tract, genitourinary tract, liver, pancreas, adrenal gland, thyroid gland, lung, trachea, spleen and thymus. {ECO:0000269|PubMed:10887190, ECO:0000269|PubMed:10894543, ECO:0000269|PubMed:10899166, ECO:0000269|PubMed:11010960}. |
Top Pathways | Neuroactive ligand-receptor interaction |
NMUR2 CRISPR/Cas9 KO Plasmid (h) - sc-404637 from Santa Cruz Biotechnology
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NMUR2 HDR Plasmid (h) - sc-404637-HDR from Santa Cruz Biotechnology
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NMUR2 Double Nickase Plasmid (h) - sc-404637-NIC from Santa Cruz Biotechnology
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NMUR2 Double Nickase Plasmid (h2) - sc-404637-NIC-2 from Santa Cruz Biotechnology
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NMUR2 CRISPR Activation Plasmid (h) - sc-404637-ACT from Santa Cruz Biotechnology
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NMUR2 CRISPR Activation Plasmid (h2) - sc-404637-ACT-2 from Santa Cruz Biotechnology
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NMUR2 Lentiviral Activation Particles (h) - sc-404637-LAC from Santa Cruz Biotechnology
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NMUR2 Lentiviral Activation Particles (h2) - sc-404637-LAC-2 from Santa Cruz Biotechnology
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NMUR2 siRNA (h) - sc-61211 from Santa Cruz Biotechnology
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NMUR2 shRNA Plasmid (h) - sc-61211-SH from Santa Cruz Biotechnology
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NMUR2 shRNA (h) Lentiviral Particles - sc-61211-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN15384 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15384 from Sigma-Aldrich
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NMUR2 siRNA (Human) - CRJ1226 from Cohesion Biosciences
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Neuromedin U R2/NMUR2 RNAi - H00056923-R01 from Novus Biologicals
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NMUR2 CRISPR/Cas9 KO Plasmid (h2) - sc-404637-KO-2 from Santa Cruz Biotechnology
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NMUR2 HDR Plasmid (h2) - sc-404637-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human NMUR2 (NM_020167.4) - SHH353332 from Creative biogene
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Human NMUR2 siRNA - orb271727 from Biorbyt
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NMUR2 shRNA Plasmid (Human) - CHJ1226 from Cohesion Biosciences
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NMUR2 miRNA 3'UTR clone - MiUTR3H-07380 from Creative biogene
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