| Gene Symbol |
KCNE5
|
| Entrez Gene |
23630
|
| Alt Symbol |
KCNE1L
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
potassium channel, voltage gated subfamily E regulatory beta subunit 5
|
| Other Description |
AMME syndrome candidate gene 2 protein|AMMECR2 protein|KCNE1-like|cardiac voltage-gated potassium channel accessory subunit 5|potassium channel subunit beta MiRP4|potassium voltage-gated channel subfamily E member 1-like protein|potassium voltage-gated channel subfamily E regulatory beta subunit 5|potassium voltage-gated channel, Isk-related family, member 1-like
|
| Swissprots |
Q9UJ90 Q5JWV7
|
| Accessions |
ABQ01242 EAX02676 Q9UJ90 AF086499 AJ012743 CAB58359 AK223306 BAD97026 AK314923 BAG37431 BC035330 AAH35330 DQ192294 ABB00307 DQ891287 ABM82213 DQ894471 ABM85397 DQ896649 ABM87648 DQ896656 ABM87655 DQ896659 ABM87658 DQ896664 ABM87663 EF535525 ABQ08564 NM_012282 NP_036414
|
| Function |
Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. {ECO:0000269|PubMed:12324418}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Tissue Specificity |
Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta. {ECO:0000269|PubMed:10493825}.
|