Gene Symbol | KCNE5 |
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Entrez Gene | 23630 |
Alt Symbol | KCNE1L |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, voltage gated subfamily E regulatory beta subunit 5 |
Other Description | AMME syndrome candidate gene 2 protein|AMMECR2 protein|KCNE1-like|cardiac voltage-gated potassium channel accessory subunit 5|potassium channel subunit beta MiRP4|potassium voltage-gated channel subfamily E member 1-like protein|potassium voltage-gated channel subfamily E regulatory beta subunit 5|potassium voltage-gated channel, Isk-related family, member 1-like |
Swissprots | Q9UJ90 Q5JWV7 |
Accessions | ABQ01242 EAX02676 Q9UJ90 AF086499 AJ012743 CAB58359 AK223306 BAD97026 AK314923 BAG37431 BC035330 AAH35330 DQ192294 ABB00307 DQ891287 ABM82213 DQ894471 ABM85397 DQ896649 ABM87648 DQ896656 ABM87655 DQ896659 ABM87658 DQ896664 ABM87663 EF535525 ABQ08564 NM_012282 NP_036414 |
Function | Potassium channel ancillary subunit that is essential for generation of some native K(+) currents by virtue of formation of heteromeric ion channel complex with voltage-gated potassium (Kv) channel pore-forming alpha subunits. Functions as an inhibitory beta-subunit of the repolarizing cardiac potassium ion channel KCNQ1. {ECO:0000269|PubMed:12324418}. |
Subcellular Location | Membrane; Single-pass type I membrane protein. |
Tissue Specificity | Highly expressed in heart, skeletal muscle, brain, spinal cord and placenta. {ECO:0000269|PubMed:10493825}. |
KCNE1L CRISPR/Cas9 KO Plasmid (h) - sc-407196 from Santa Cruz Biotechnology
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KCNE1L HDR Plasmid (h) - sc-407196-HDR from Santa Cruz Biotechnology
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KCNE1L Double Nickase Plasmid (h) - sc-407196-NIC from Santa Cruz Biotechnology
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KCNE1L Double Nickase Plasmid (h2) - sc-407196-NIC-2 from Santa Cruz Biotechnology
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KCNE1L CRISPR Activation Plasmid (h) - sc-407196-ACT from Santa Cruz Biotechnology
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KCNE1L CRISPR Activation Plasmid (h2) - sc-407196-ACT-2 from Santa Cruz Biotechnology
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KCNE1L Lentiviral Activation Particles (h) - sc-407196-LAC from Santa Cruz Biotechnology
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KCNE1L Lentiviral Activation Particles (h2) - sc-407196-LAC-2 from Santa Cruz Biotechnology
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KCNE1L siRNA (h) - sc-91235 from Santa Cruz Biotechnology
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KCNE1L shRNA Plasmid (h) - sc-91235-SH from Santa Cruz Biotechnology
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KCNE1L shRNA (h) Lentiviral Particles - sc-91235-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10933 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10933 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR12498 from Sigma-Aldrich
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KCNE1L siRNA (Human) - CRH8408 from Cohesion Biosciences
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KCNE1L, siRNA - MBS829993 from MyBioSource
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shRNA set against Human KCNE1L (NM_012282.2) - SHH322927 from Creative biogene
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shRNA set against Human KCNE1L(NM_012282.2) - SHL182154 from Creative biogene
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KCNE1L shRNA Plasmid (Human) - CHH8408 from Cohesion Biosciences
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KCNE1L miRNA 3'UTR clone - MiUTR1H-05104 from Creative biogene
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