| Gene Symbol |
DERA
|
| Entrez Gene |
51071
|
| Alt Symbol |
CGI-26, DEOC
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
deoxyribose-phosphate aldolase (putative)
|
| Other Description |
2-deoxy-D-ribose 5-phosphate aldolase|2-deoxyribose-5-phosphate aldolase homolog|deoxyriboaldolase|deoxyribose-phosphate aldolase|phosphodeoxyriboaldolase|putative deoxyribose-phosphate aldolase
|
| Swissprots |
Q9Y315 Q6PHW2 Q53HN9
|
| Accessions |
EAW96357 EAW96358 EAW96359 Q9Y315 AF132960 AAD27735 AK024614 AK222541 BAD96261 AK296697 BAG59291 AK309182 BC041328 BC056234 AAH56234 BC152913 AAI52914 BU928832 CB851336 NM_001300779 NP_001287708 NM_015954 NP_057038
|
| Function |
Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation. {ECO:0000269|PubMed:25229427}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:25229427}. Cytoplasmic granule {ECO:0000269|PubMed:25229427}. Nucleus {ECO:0000269|PubMed:25229427}. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation. {ECO:0000269|PubMed:25229427}.
|
| Tissue Specificity |
Mainly expressed in liver, lung and colon. {ECO:0000269|PubMed:25229427}.
|
| Top Pathways |
Pentose phosphate pathway
|