Gene Symbol | DERA |
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Entrez Gene | 51071 |
Alt Symbol | CGI-26, DEOC |
Species | Human |
Gene Type | protein-coding |
Description | deoxyribose-phosphate aldolase (putative) |
Other Description | 2-deoxy-D-ribose 5-phosphate aldolase|2-deoxyribose-5-phosphate aldolase homolog|deoxyriboaldolase|deoxyribose-phosphate aldolase|phosphodeoxyriboaldolase|putative deoxyribose-phosphate aldolase |
Swissprots | Q9Y315 Q6PHW2 Q53HN9 |
Accessions | EAW96357 EAW96358 EAW96359 Q9Y315 AF132960 AAD27735 AK024614 AK222541 BAD96261 AK296697 BAG59291 AK309182 BC041328 BC056234 AAH56234 BC152913 AAI52914 BU928832 CB851336 NM_001300779 NP_001287708 NM_015954 NP_057038 |
Function | Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation. {ECO:0000269|PubMed:25229427}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:25229427}. Cytoplasmic granule {ECO:0000269|PubMed:25229427}. Nucleus {ECO:0000269|PubMed:25229427}. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation. {ECO:0000269|PubMed:25229427}. |
Tissue Specificity | Mainly expressed in liver, lung and colon. {ECO:0000269|PubMed:25229427}. |
Top Pathways | Pentose phosphate pathway |
DERA (D-13) - sc-107517 from Santa Cruz Biotechnology
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DERA (G-12) - sc-107518 from Santa Cruz Biotechnology
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Anti-DERA antibody - N-terminal - ab93472 from Abcam
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Anti-DERA Antibody (N-Terminus, AP) - LS-C225085 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, Biotin) - LS-C225088 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, Azide-free, HRP) - LS-C225090 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, APC) - LS-C225087 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, FITC) - LS-C225089 from LifeSpan Bioscience
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Anti-DERA Antibody (aa39-88) - LS-C187293 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, PE) - LS-C225092 from LifeSpan Bioscience
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Anti-DERA Antibody (N-Terminus, Azide-free) - LS-C327183 from LifeSpan Bioscience
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Anti-DERA Antibody (aa12-41) - LS-C167366 from LifeSpan Bioscience
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DERA Antibody - NBP2-31784 from Novus Biologicals
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ANTI-DERA (N-TERM) antibody produced in rabbit - SAB1301182 from Sigma-Aldrich
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Anti-DERA antibody produced in rabbit - HPA059619 from Sigma-Aldrich
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DERA Antibody - N-terminal region (ARP63480_P050) - ARP63480_P050 from Aviva Systems Biology
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DERA-Antibody-N-term - AP8764a from Abgent, a WuXi AppTec company
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DERA Antibody - N-terminal region (OAAB05361) - OAAB05361 from Aviva Systems Biology
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DERA antibody, N-term - GTX81043 from GeneTex
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DERA (N-term) antibody - AP17986PU-N from Acris Antibodies
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DERA antibody - H00051071-B01P from Acris Antibodies
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DERA, Polyclonal Antibody - MBS6010309 from MyBioSource
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DERA-Antibody-N-terminal-region-AI14967 - AI14967 from Abgent, a WuXi AppTec company
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DERA, Polyclonal Antibody - MBS9206383 from MyBioSource
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DERA antibody - TA343318 from Acris Antibodies
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