Gene Symbol | BATF3 |
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Entrez Gene | 55509 |
Alt Symbol | JDP1, JUNDM1, SNFT |
Species | Human |
Gene Type | protein-coding |
Description | basic leucine zipper transcription factor, ATF-like 3 |
Other Description | 21 kDa small nuclear factor isolated from T-cells|21-kD small nuclear factor isolated from T cells|B-ATF-3|Jun dimerization protein 1|Jun dimerization protein p21SNFT|basic leucine zipper transcriptional factor ATF-like 3 |
Swissprots | Q9NR55 |
Accessions | EAW93381 Q9NR55 AF255346 AAF73966 AK093671 AK094854 BC117489 AAI17490 BC117491 AAI17492 BG184570 HQ258061 ADR82815 XR_921869 NM_018664 NP_061134 |
Function | AP-1 family transcription factor that controls the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. Required for development of CD8-alpha(+) classical dendritic cells (cDCs) and related CD103(+) dendritic cells that cross-present antigens to CD8 T-cells and produce interleukin-12 (IL12) in response to pathogens (By similarity). Acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes. {ECO:0000250, ECO:0000269|PubMed:10878360, ECO:0000269|PubMed:12087103, ECO:0000269|PubMed:15467742}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00978, ECO:0000269|PubMed:12087103}. |
SNFT CRISPR/Cas9 KO Plasmid (h) - sc-403344 from Santa Cruz Biotechnology
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SNFT HDR Plasmid (h) - sc-403344-HDR from Santa Cruz Biotechnology
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SNFT Double Nickase Plasmid (h) - sc-403344-NIC from Santa Cruz Biotechnology
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SNFT Double Nickase Plasmid (h2) - sc-403344-NIC-2 from Santa Cruz Biotechnology
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SNFT CRISPR Activation Plasmid (h) - sc-403344-ACT from Santa Cruz Biotechnology
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SNFT CRISPR Activation Plasmid (h2) - sc-403344-ACT-2 from Santa Cruz Biotechnology
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SNFT Lentiviral Activation Particles (h) - sc-403344-LAC from Santa Cruz Biotechnology
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SNFT Lentiviral Activation Particles (h2) - sc-403344-LAC-2 from Santa Cruz Biotechnology
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SNFT siRNA (h) - sc-88553 from Santa Cruz Biotechnology
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SNFT shRNA Plasmid (h) - sc-88553-SH from Santa Cruz Biotechnology
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SNFT shRNA (h) Lentiviral Particles - sc-88553-V from Santa Cruz Biotechnology
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BATF3 RNAi - H00055509-R01 from Novus Biologicals
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MISSION® esiRNA - EHU153831 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN3871 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3871 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03116 from Sigma-Aldrich
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BATF3 siRNA (Human) - CRJ0718 from Cohesion Biosciences
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BATF3 - MBS8202656 from MyBioSource
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shRNA set against Human BATF3 (NM_018664.2) - SHH244998 from Creative biogene
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Human BATF3 siRNA - orb271219 from Biorbyt
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BATF3 shRNA Plasmid (Human) - CHJ0718 from Cohesion Biosciences
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BATF3 miRNA 3'UTR clone - MiUTR4H-TG00733 from Creative biogene
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