Gene Symbol | EOMES |
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Entrez Gene | 8320 |
Alt Symbol | TBR2 |
Species | Human |
Gene Type | protein-coding |
Description | eomesodermin |
Other Description | T-box brain protein 2|eomesodermin homolog |
Swissprots | Q8TAZ2 B7Z4I2 Q9UPM7 G3XAI5 B7ZA51 O95936 |
Accessions | CAB37939 CAY55962 CBX47638 EAW64387 EAW64388 O95936 AB031038 BAA83417 AK297389 BAH12568 AK297461 BAH12586 AK299499 BAH13052 AK299695 BAH13105 AK316166 BAH14537 BC025363 AAH25363 BC037568 BC131712 BM720063 BX096900 XM_005265510 XP_005265567 NM_001278182 NP_001265111 NM_001278183 NP_001265112 NM_005442 NP_005433 |
Function | Functions as a transcriptional activator playing a crucial role during development. Functions in trophoblast differentiation and later in gastrulation, regulating both mesoderm delamination and endoderm specification. Plays a role in brain development being required for the specification and the proliferation of the intermediate progenitor cells and their progeny in the cerebral cortex. Also involved in the differentiation of CD8+ T-cells during immune response regulating the expression of lytic effector genes. {ECO:0000269|PubMed:17353897, ECO:0000269|PubMed:17566017}. |
Subcellular Location | Nucleus {ECO:0000305}. |
Tissue Specificity | Expressed in CD8+ T-cells. {ECO:0000269|PubMed:17566017}. |
Human TBR2 / Eomes protein fragment - ab152851 from Abcam
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Human TBR2 / Eomes protein fragment - ab152852 from Abcam
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Mouse TBR2 / Eomes peptide - ab25698 from Abcam
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Eomesodermin / EOMES Antibody Blocking Peptide - LS-E10478 from LifeSpan Bioscience
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Eomesodermin / EOMES Antibody Blocking Peptide - LS-E13902 from LifeSpan Bioscience
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Eomesodermin / EOMES Antibody Blocking Peptide - LS-E13593 from LifeSpan Bioscience
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Eomesodermin / EOMES Antibody Blocking Peptide - LS-E7016 from LifeSpan Bioscience
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EOMES Partial Recombinant Protein - H00008320-Q01 from Novus Biologicals
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Recombinant Human EOMES Protein - H00008320-Q03 from Novus Biologicals
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EOMES-TBR2-Antibody-N-term-Blocking-peptide - BP2703a from Abgent, a WuXi AppTec company
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EOMES Blocking Peptide - abx063462 from Abbexa
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EOMES / TBR2 - H00008320-Q01-10 from Acris Antibodies
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EOMES / TBR2 - H00008320-Q01-25 from Acris Antibodies
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EOMES / TBR2 - H00008320-Q03 from Acris Antibodies
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EOMES / TBR2 - H00008320-Q03-10 from Acris Antibodies
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EOMES / TBR2 - H00008320-Q03-25 from Acris Antibodies
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Recombinant Eomesodermin (EOMES) - RPK459Hu01 from Uscn Life Science Inc.
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EOMES Blocking Peptide - CBP2268 from Cohesion Biosciences
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EOMES (P108) Peptide - BS9048P from Bioworld Technology
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Recombinant Eomesodermin (EOMES) - RPK459Hu01 from Cloud-clone
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Recombinant Human Eomesodermin homolog(EOMES) - CSB-YP007701HU CSB-EP007701HU CSB-BP007701HU CSB-MP007701HU from Cusabio
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EOMES Recombinant Protein Antigen - NBP1-80699PEP from Novus Biologicals
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EOMES-Blocking-PeptideN-term - BP19703a from Abgent, a WuXi AppTec company
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EOMES Peptide, Human - M34GP04965H from Creative Peptides
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Recombinant Eomesodermin (EOMES) - RPU50710 from Biomatik
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