| Gene Symbol |
ELMOD2
|
| Entrez Gene |
255520
|
| Alt Symbol |
9830169G11Rik
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ELMO/CED-12 domain containing 2
|
| Other Description |
ELMO domain containing 2|ELMO domain-containing protein 2
|
| Swissprots |
D3DNZ0 Q8IZ81 B2R712
|
| Accessions |
CAR81484 CAS91500 EAX05096 EAX05097 Q8IZ81 AK021525 AK093087 AK095357 AK312800 BAG35659 BC015168 AAH15168 BX499240 BX648349 BX648843 DA797584 DB278612 XM_005262885 XP_005262942 XM_005262886 XP_005262943 XM_011531818 XP_011530120 XM_011531819 XP_011530121 XR_938716 NM_153702 NP_714913
|
| Function |
Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. {ECO:0000269|PubMed:17452337, ECO:0000269|PubMed:19966137}.
|
| Tissue Specificity |
Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls. {ECO:0000269|PubMed:16773575, ECO:0000269|PubMed:17452337}.
|