Gene Symbol | ELMOD2 |
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Entrez Gene | 255520 |
Alt Symbol | 9830169G11Rik |
Species | Human |
Gene Type | protein-coding |
Description | ELMO/CED-12 domain containing 2 |
Other Description | ELMO domain containing 2|ELMO domain-containing protein 2 |
Swissprots | D3DNZ0 Q8IZ81 B2R712 |
Accessions | CAR81484 CAS91500 EAX05096 EAX05097 Q8IZ81 AK021525 AK093087 AK095357 AK312800 BAG35659 BC015168 AAH15168 BX499240 BX648349 BX648843 DA797584 DB278612 XM_005262885 XP_005262942 XM_005262886 XP_005262943 XM_011531818 XP_011530120 XM_011531819 XP_011530121 XR_938716 NM_153702 NP_714913 |
Function | Acts as a GTPase-activating protein (GAP) toward guanine nucleotide exchange factors like ARL2, ARL3, ARF1 and ARF6, but not for GTPases outside the Arf family. Regulates IFN-related antiviral responses. {ECO:0000269|PubMed:17452337, ECO:0000269|PubMed:19966137}. |
Tissue Specificity | Alveolar cells (morphologically type II cells) and alveolar macrophages (at protein level). Expressed in brain, colon, heart, kidney, liver, lung, muscle, placenta, small intestine, spleen, stomach and testis. In lung it is expressed in alveolar macrophages and alveolar walls. {ECO:0000269|PubMed:16773575, ECO:0000269|PubMed:17452337}. |
ELMOD2 CRISPR/Cas9 KO Plasmid (h) - sc-410398 from Santa Cruz Biotechnology
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ELMOD2 HDR Plasmid (h) - sc-410398-HDR from Santa Cruz Biotechnology
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ELMOD2 Double Nickase Plasmid (h) - sc-410398-NIC from Santa Cruz Biotechnology
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ELMOD2 Double Nickase Plasmid (h2) - sc-410398-NIC-2 from Santa Cruz Biotechnology
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ELMOD2 CRISPR Activation Plasmid (h) - sc-410398-ACT from Santa Cruz Biotechnology
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ELMOD2 CRISPR Activation Plasmid (h2) - sc-410398-ACT-2 from Santa Cruz Biotechnology
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ELMOD2 Lentiviral Activation Particles (h) - sc-410398-LAC from Santa Cruz Biotechnology
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ELMOD2 Lentiviral Activation Particles (h2) - sc-410398-LAC-2 from Santa Cruz Biotechnology
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ELMOD2 siRNA (h) - sc-77263 from Santa Cruz Biotechnology
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ELMOD2 shRNA Plasmid (h) - sc-77263-SH from Santa Cruz Biotechnology
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ELMOD2 shRNA (h) Lentiviral Particles - sc-77263-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU050991 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN7816 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7816 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03285 from Sigma-Aldrich
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ELMOD2 siRNA (Human) - CRJ6724 from Cohesion Biosciences
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ELMOD2 - MBS8201365 from MyBioSource
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shRNA set against Human ELMOD2 (NM_153702.3) - SHH285197 from Creative biogene
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Human ELMOD2 siRNA - orb277225 from Biorbyt
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ELMOD2 shRNA Plasmid (Human) - CHJ6724 from Cohesion Biosciences
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ELMOD2 miRNA 3'UTR clone - MiUTR3H-11079 from Creative biogene
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