| Gene Symbol |
LRFN1
|
| Entrez Gene |
57622
|
| Alt Symbol |
SALM2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leucine rich repeat and fibronectin type III domain containing 1
|
| Other Description |
CTC-246B18.8|leucine-rich repeat and fibronectin type III domain-containing protein 1|synaptic adhesion-like molecule 2
|
| Swissprots |
Q8TBS9 Q9P244
|
| Accessions |
CCQ43654 EAW56872 Q9P244 AB040917 BAA96008 BC014678 AAH14678 BC025310 AAH25310 BC040681 HG510795 XM_005259102 XP_005259159 NM_020862 NP_065913
|
| Function |
Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Detected in excitatory, but not inhibitory, synaptic plasma membrane. {ECO:0000250}.
|