Gene Symbol | LRFN1 |
---|---|
Entrez Gene | 57622 |
Alt Symbol | SALM2 |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat and fibronectin type III domain containing 1 |
Other Description | CTC-246B18.8|leucine-rich repeat and fibronectin type III domain-containing protein 1|synaptic adhesion-like molecule 2 |
Swissprots | Q8TBS9 Q9P244 |
Accessions | CCQ43654 EAW56872 Q9P244 AB040917 BAA96008 BC014678 AAH14678 BC025310 AAH25310 BC040681 HG510795 XM_005259102 XP_005259159 NM_020862 NP_065913 |
Function | Promotes neurite outgrowth in hippocampal neurons. Involved in the regulation and maintenance of excitatory synapses. Induces the clustering of excitatory postsynaptic proteins, including DLG4, DLGAP1, GRIA1 and GRIN1 (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell junction, synapse {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Note=Detected in excitatory, but not inhibitory, synaptic plasma membrane. {ECO:0000250}. |
LRFN1 CRISPR/Cas9 KO Plasmid (h) - sc-412861 from Santa Cruz Biotechnology
|
||||||||
LRFN1 HDR Plasmid (h) - sc-412861-HDR from Santa Cruz Biotechnology
|
||||||||
LRFN1 Double Nickase Plasmid (h) - sc-412861-NIC from Santa Cruz Biotechnology
|
||||||||
LRFN1 Double Nickase Plasmid (h2) - sc-412861-NIC-2 from Santa Cruz Biotechnology
|
||||||||
LRFN1 CRISPR Activation Plasmid (h) - sc-412861-ACT from Santa Cruz Biotechnology
|
||||||||
LRFN1 CRISPR Activation Plasmid (h2) - sc-412861-ACT-2 from Santa Cruz Biotechnology
|
||||||||
LRFN1 Lentiviral Activation Particles (h) - sc-412861-LAC from Santa Cruz Biotechnology
|
||||||||
LRFN1 Lentiviral Activation Particles (h2) - sc-412861-LAC-2 from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU118571 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN12673 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12673 from Sigma-Aldrich
|
||||||||
LRFN1 siRNA (Human) - CRJ1589 from Cohesion Biosciences
|
||||||||
shRNA set against Human Lrfn1 (NM_020862.1) - SHH333775 from Creative biogene
|
||||||||
Human LRFN1 siRNA - orb272090 from Biorbyt
|
||||||||
LRFN1 shRNA Plasmid (Human) - CHJ1589 from Cohesion Biosciences
|