| Gene Symbol |
SLC2A9
|
| Entrez Gene |
56606
|
| Alt Symbol |
GLUT9, GLUTX, UAQTL2, URATv1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 2 (facilitated glucose transporter), member 9
|
| Other Description |
GLUT-9|glucose transporter type 9|human glucose transporter-like protein-9|solute carrier family 2, facilitated glucose transporter member 9|urate voltage-driven efflux transporter 1
|
| Swissprots |
Q8WV30 Q4W5D1 Q96P00 Q0VGC4 Q9NRM0
|
| Accessions |
AAY41052 EAW92681 EAW92682 EAW92683 Q9NRM0 AF210317 AAF85942 AF421859 AAL16939 AK096819 AK310895 AL572022 BC018897 AAH18897 BC110414 AAI10415 BI821650 CD629819 CD629822 DQ786220 DQ891942 ABM82868 DQ895129 ABM86055 XM_006713968 XP_006714031 XM_006713969 XP_006714032 XM_011513856 XP_011512158 XM_011513857 XP_011512159 XM_011513858 XP_011512160 XM_011513859 XP_011512161 XM_011513860 XP_011512162 XM_011513861 XP_011512163 XM_011513862 XP_011512164 XM_011513863 XP_011512165 XM_011513864 XP_011512166 XM_011513865 XP_011512167 XM_011513866 XP_011512168 XM_011513867 XP_011512169 XM_011513868 XP_011512170 XR_925341 NM_001001290 NP_001001290 NM_020041 NP_064425
|
| Function |
Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate. {ECO:0000269|PubMed:14739288, ECO:0000269|PubMed:18327257}.
|
| Subcellular Location |
Isoform 1: Basolateral cell membrane {ECO:0000269|PubMed:14739288, ECO:0000269|PubMed:24409316}; Multi- pass membrane protein {ECO:0000269|PubMed:14739288}.
|
| Tissue Specificity |
Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level). {ECO:0000269|PubMed:11991658, ECO:0000269|PubMed:24409316}.
|