SLC2A9
| Gene Symbol | SLC2A9 |
|---|---|
| Entrez Gene | 56606 |
| Alt Symbol | GLUT9, GLUTX, UAQTL2, URATv1 |
| Species | Human |
| Gene Type | protein-coding |
| Description | solute carrier family 2 (facilitated glucose transporter), member 9 |
| Other Description | GLUT-9|glucose transporter type 9|human glucose transporter-like protein-9|solute carrier family 2, facilitated glucose transporter member 9|urate voltage-driven efflux transporter 1 |
| Swissprots | Q8WV30 Q4W5D1 Q96P00 Q0VGC4 Q9NRM0 |
| Accessions | AAY41052 EAW92681 EAW92682 EAW92683 Q9NRM0 AF210317 AAF85942 AF421859 AAL16939 AK096819 AK310895 AL572022 BC018897 AAH18897 BC110414 AAI10415 BI821650 CD629819 CD629822 DQ786220 DQ891942 ABM82868 DQ895129 ABM86055 XM_006713968 XP_006714031 XM_006713969 XP_006714032 XM_011513856 XP_011512158 XM_011513857 XP_011512159 XM_011513858 XP_011512160 XM_011513859 XP_011512161 XM_011513860 XP_011512162 XM_011513861 XP_011512163 XM_011513862 XP_011512164 XM_011513863 XP_011512165 XM_011513864 XP_011512166 XM_011513865 XP_011512167 XM_011513866 XP_011512168 XM_011513867 XP_011512169 XM_011513868 XP_011512170 XR_925341 NM_001001290 NP_001001290 NM_020041 NP_064425 |
| Function | Transport urate and fructose. May have a role in the urate reabsorption by proximal tubules. Also transports glucose at low rate. {ECO:0000269|PubMed:14739288, ECO:0000269|PubMed:18327257}. |
| Subcellular Location | Isoform 1: Basolateral cell membrane {ECO:0000269|PubMed:14739288, ECO:0000269|PubMed:24409316}; Multi- pass membrane protein {ECO:0000269|PubMed:14739288}. |
| Tissue Specificity | Most strongly expressed in basolateral membranes of proximal renal tubular cells, liver and placenta. Also detected in lung, blood leukocytes, heart skeletal muscle and chondrocytes from articular cartilage. Isoform 2 is only detected in the apical membranes of polarized renal tubular cells and placenta. Isoform 1 and isoform 2 are detected in kidney membrane (at protein level). {ECO:0000269|PubMed:11991658, ECO:0000269|PubMed:24409316}. |
Glut9 CRISPR/Cas9 KO Plasmid (h) - sc-406232 from Santa Cruz Biotechnology
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Glut9 HDR Plasmid (h) - sc-406232-HDR from Santa Cruz Biotechnology
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Glut9 Double Nickase Plasmid (h) - sc-406232-NIC from Santa Cruz Biotechnology
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Glut9 Double Nickase Plasmid (h2) - sc-406232-NIC-2 from Santa Cruz Biotechnology
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Glut9 CRISPR Activation Plasmid (h) - sc-406232-ACT from Santa Cruz Biotechnology
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Glut9 CRISPR Activation Plasmid (h2) - sc-406232-ACT-2 from Santa Cruz Biotechnology
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Glut9 Lentiviral Activation Particles (h) - sc-406232-LAC from Santa Cruz Biotechnology
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Glut9 Lentiviral Activation Particles (h2) - sc-406232-LAC-2 from Santa Cruz Biotechnology
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Glut9 siRNA (h) - sc-105399 from Santa Cruz Biotechnology
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Glut9 shRNA Plasmid (h) - sc-105399-SH from Santa Cruz Biotechnology
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Glut9 shRNA (h) Lentiviral Particles - sc-105399-V from Santa Cruz Biotechnology
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GLUT9 RNAi - H00056606-R02 from Novus Biologicals
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MISSION® esiRNA - EHU070431 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19554 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19554 from Sigma-Aldrich
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SLC2A9 siRNA (Human) - CRJ1151 from Cohesion Biosciences
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GLUT9 RNAi - H00056606-R01 from Novus Biologicals
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SLC2A9 - MBS8215407 from MyBioSource
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Glut9 CRISPR/Cas9 KO Plasmid (h2) - sc-406232-KO-2 from Santa Cruz Biotechnology
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Glut9 HDR Plasmid (h2) - sc-406232-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human SLC2A9 (NM_020041.2) - SHH410340 from Creative biogene
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shRNA set against Human SLC2A9(NM_001001290.1) - SHL005958 from Creative biogene
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shRNA set against Human SLC2A9(NM_020041.2) - SHL005976 from Creative biogene
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Human SLC2A9 siRNA - orb271652 from Biorbyt
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SLC2A9 shRNA Plasmid (Human) - CHJ1151 from Cohesion Biosciences
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