Gene Symbol |
SEC63
|
Entrez Gene |
11231
|
Alt Symbol |
DNAJC23, ERdj2, PRO2507, SEC63L
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
SEC63 homolog (S. cerevisiae)
|
Other Description |
translocation protein SEC63 homolog
|
Swissprots |
O95380 Q9UGP8 Q5THN4 Q8IWL0 Q9NTE0 Q86VS9
|
Accessions |
EAW48392 Q9UGP8 AF100141 AAC83375 AF119883 AAF69637 AI559292 AJ011779 CAB46275 AJ420532 AK001465 AK027374 BAG51309 AK074835 BAG52012 AL137338 CAB70701 BC001153 BC009066 BC023598 AAH23598 BC047221 AAH47221 BC048287 AAH48287 BE972247 BM764168 DB049187 X75689 XM_011535399 XP_011533701 NM_007214 NP_009145 NM_018529
|
Function |
Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane.
|
Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Widely expressed, with high levels in the liver. {ECO:0000269|PubMed:15133510}.
|
Top Pathways |
Protein export, Protein processing in endoplasmic reticulum
|