Gene Symbol | SEC63 |
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Entrez Gene | 11231 |
Alt Symbol | DNAJC23, ERdj2, PRO2507, SEC63L |
Species | Human |
Gene Type | protein-coding |
Description | SEC63 homolog (S. cerevisiae) |
Other Description | translocation protein SEC63 homolog |
Swissprots | O95380 Q9UGP8 Q5THN4 Q8IWL0 Q9NTE0 Q86VS9 |
Accessions | EAW48392 Q9UGP8 AF100141 AAC83375 AF119883 AAF69637 AI559292 AJ011779 CAB46275 AJ420532 AK001465 AK027374 BAG51309 AK074835 BAG52012 AL137338 CAB70701 BC001153 BC009066 BC023598 AAH23598 BC047221 AAH47221 BC048287 AAH48287 BE972247 BM764168 DB049187 X75689 XM_011535399 XP_011533701 NM_007214 NP_009145 NM_018529 |
Function | Required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membrane. |
Subcellular Location | Endoplasmic reticulum membrane; Multi-pass membrane protein. |
Tissue Specificity | Widely expressed, with high levels in the liver. {ECO:0000269|PubMed:15133510}. |
Top Pathways | Protein export, Protein processing in endoplasmic reticulum |
Sec63 CRISPR/Cas9 KO Plasmid (h) - sc-407766 from Santa Cruz Biotechnology
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Sec63 HDR Plasmid (h) - sc-407766-HDR from Santa Cruz Biotechnology
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Sec63 Double Nickase Plasmid (h) - sc-407766-NIC from Santa Cruz Biotechnology
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Sec63 Double Nickase Plasmid (h2) - sc-407766-NIC-2 from Santa Cruz Biotechnology
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Sec63 CRISPR Activation Plasmid (h) - sc-407766-ACT from Santa Cruz Biotechnology
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Sec63 CRISPR Activation Plasmid (h2) - sc-407766-ACT-2 from Santa Cruz Biotechnology
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Sec63 Lentiviral Activation Particles (h) - sc-407766-LAC from Santa Cruz Biotechnology
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Sec63 Lentiviral Activation Particles (h2) - sc-407766-LAC-2 from Santa Cruz Biotechnology
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Sec63 siRNA (h) - sc-41288 from Santa Cruz Biotechnology
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Sec63 shRNA Plasmid (h) - sc-41288-SH from Santa Cruz Biotechnology
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Sec63 shRNA (h) Lentiviral Particles - sc-41288-V from Santa Cruz Biotechnology
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SEC63 RNAi - H00011231-R02 from Novus Biologicals
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MISSION® esiRNA - EHU108451 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN19044 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19044 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09380 from Sigma-Aldrich
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SEC63 siRNA (Human) - CRH7697 from Cohesion Biosciences
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SEC63 - MBS8205172 from MyBioSource
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Human SEC63 siRNA - orb268199 from Biorbyt
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SEC63 shRNA Plasmid (Human) - CHH7697 from Cohesion Biosciences
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SEC63 miRNA 3'UTR clone - MiUTR4H-TG07894 from Creative biogene
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