| Gene Symbol |
PYDC2
|
| Entrez Gene |
152138
|
| Alt Symbol |
POP2, cPOP2
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
pyrin domain containing 2
|
| Other Description |
pyrin domain-containing protein 2|pyrin-only protein 2
|
| Swissprots |
Q56P42
|
| Accessions |
Q56P42 AY858112 AAX54598 NM_001083308 NP_001076777
|
| Function |
Inhibits NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA. Disrupts the interaction between PYCARD and NLRP3. {ECO:0000269|PubMed:17339483}.
|
| Subcellular Location |
Cytoplasm {ECO:0000269|PubMed:17339483}. Nucleus {ECO:0000269|PubMed:17339483}.
|
| Tissue Specificity |
Predominantly expressed in peripheral blood. Weakly expressed in testis. {ECO:0000269|PubMed:17339483}.
|