Gene Symbol | PYDC2 |
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Entrez Gene | 152138 |
Alt Symbol | POP2, cPOP2 |
Species | Human |
Gene Type | protein-coding |
Description | pyrin domain containing 2 |
Other Description | pyrin domain-containing protein 2|pyrin-only protein 2 |
Swissprots | Q56P42 |
Accessions | Q56P42 AY858112 AAX54598 NM_001083308 NP_001076777 |
Function | Inhibits NF-kappa-B signaling distally by affecting the nuclear accumulation of RELA. Disrupts the interaction between PYCARD and NLRP3. {ECO:0000269|PubMed:17339483}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:17339483}. Nucleus {ECO:0000269|PubMed:17339483}. |
Tissue Specificity | Predominantly expressed in peripheral blood. Weakly expressed in testis. {ECO:0000269|PubMed:17339483}. |
CompoZr® Knockout ZFN Kit - CKOZFN17771 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17771 from Sigma-Aldrich
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PYDC2 siRNA (Human) - CRJ5732 from Cohesion Biosciences
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shRNA set against Human PYDC2 (NM_001083308.1) - SHH387416 from Creative biogene
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PYDC2 shRNA Plasmid (Human) - CHJ5732 from Cohesion Biosciences
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PYDC2 miRNA 3'UTR clone - MiUTR1H-08096 from Creative biogene
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