KCNJ10

Gene Symbol KCNJ10
Entrez Gene 3766
Alt Symbol BIRK-10, KCNJ13-PEN, KIR1.2, KIR4.1, SESAME
Species Human
Gene Type protein-coding
Description potassium channel, inwardly rectifying subfamily J, member 10
Other Description ATP-dependent inwardly rectifying potassium channel Kir4.1|ATP-sensitive inward rectifier potassium channel 10|glial ATP-dependent inwardly rectifying potassium channel KIR4.1|inward rectifier K(+) channel Kir1.2|inward rectifier K+ channel KIR1.2|potassium channel, inwardly rectifying subfamily J member 10|potassium inwardly-rectifying channel, subfamily J, member 10
Swissprots Q8N4I7 P78508 Q92808 Q5VUT9 A3KME7
Accessions AAC50923 AAK27517 AAL89708 EAW52748 EAW52749 EAW52750 P78508 AK312383 BAG35301 BC034036 AAH34036 BC037840 BC131627 AAI31628 BE466069 BM675618 DA958759 DQ892392 ABM83318 DQ895607 ABM86533 U52155 AAB07046 U73193 AAC50924 NM_002241 NP_002232
Function May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity). {ECO:0000250}.
Subcellular Location Membrane; Multi-pass membrane protein.
Top Pathways Gastric acid secretion

KIR4.1 (G-19) - sc-23637 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
KIR4.1 (G-19): sc-23637. Immunofluorescence staining of methanol-fixed Sol8 cells showing membrane localization.

Anti-Kir4.1 antibody - ab105102 from Abcam

Prices $378.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
ICC/IF image of ab105102 stained PC12 cells. The cells were 5% formaldehyde fixed (10 min) and then incubated in 1%BSA / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab105102, 1/200 dilution) overnight at +4°C. The secondary antibody (green) was ab96931, DyLight® 488 donkey anti-goat IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM

Anti-Kir4.1 antibody - ab101064 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Kir4.1 antibody (ab101064) at 1 µg/ml + Spinal Cord (Mouse) Tissue Lysate at 10 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Kir4.1 antibody - ab130707 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab130707 staining Kir4.1 in zebrafish retina sections by IHC-Fr. The tissue was fixed with paraformaldehyde and an antigen retrieval step was performed with sodium citrate pH 6. Blocking of the sample was done with 5% BSA in PBS containing 01% Tween 20 and 0.5% Triton X, for 60 minutes at 23°C, followed by staining with ab130707 at 1/100 in blocking solution for 16h at 4°C. An alexa 488 conjugated goat anti-rabbit polyclonal antibody at 1/1000 was used as the secondary antibody. Nuclei are stained in blue with DAPI. Kir4.1 expression can be observed in Muller cells (in green).See Abreview

Anti-Kir4.1 antibody - ab192406 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Kir4.1 antibody (ab192406)Lane 1 : Jurkat whole cell lysateLane 2 : Mouse brain tissue lysateLane 3 : Rat brain tissue lysate

Anti-Kir4.1 antibody - ab55380 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
ab55380 staining Kir4.1 in zebrafish retina sections by IHC-Fr. The tissue was fixed with paraformaldehyde and an antigen retrieval step was performed with sodium citrate pH 6. Blocking of the sample was done with 5% BSA in PBS, for 60 minutes at 23°C, followed by staining with ab55380 at 1/200 in blocking solution for 16h at 4°C. An alexa 647conjugated goat anti-mouse polyclonal antibody at 1/1000 was used as the secondary antibody. Nuclei are stained in blue with DAPI. Kir4.1 expression can be observed in the IPL (inner plexiform layer) in purple.See Abreview

Anti-Kir4.1 antibody - C-terminal - ab80959 from Abcam

Prices $378.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of PFA-fixed, paraffin embedded BALB/c murine ear tissue sections. Kir4.1 was stained, using ab80959 at 1/10 dilution, in the inner ear intermediate cells of stria vascularis and organ of Corti (upper panel) and middle ear epithelium (lower panel). An AlexaFluor®488-conjugated IgG (1/50) was used as the secondary antibody.

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa330-379) - LS-C94228 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, AP) - LS-C260917 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, APC) - LS-C260918 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, Biotin) - LS-C260919 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, Azide-free, HRP) - LS-C260921 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230) - LS-C329714 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, FITC) - LS-C260920 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody - LS-C340951 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa202-230, PE) - LS-C260922 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (clone 1C11) - LS-C197574 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C11
Detection limit for recombinant GST tagged KCNJ10 is approximately 0.03 ng/ml as a capture antibody.

Anti-KCNJ10 / SESAME / KIR4.1 Antibody (aa203-230) - LS-C159975 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
KCNJ10 Antibody western blot of HL-60 cell line lysates (35 ug/lane). The KCNJ10 antibody detected the KCNJ10 protein (arrow).

Anti-Sesame Protein Antibody - LS-C132069 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Chicken
Clonality Polyclonal

KCNJ10 Antibody (1C11) - H00003766-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C11
Sandwich ELISA: KCNJ10 Antibody (1C11) [H00003766-M01] - Detection limit for recombinant GST tagged KCNJ10 is approximately 0.03ng/ml as a capture antibody.

KCNJ10 Antibody - NBP1-20149 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: KCNJ10 Antibody [NBP1-20149] - WB on mouse tissue lysate. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:3000 incubated at 4C overnight.

KCNJ10 Antibody - NBP1-70371 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
Western Blot: KCNJ10 Antibody [NBP1-70371] - WB on rat spinal cord lysate. Primary antibody was used at 1:500 dilution incubated overnight at 4C.

KCNJ10 Antibody - H00003766-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Kir4.1 Polyclonal Antibody - bs-2084R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Monoclonal Anti-KCNJ10 antibody produced in mouse - WH0003766M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 1C11
<B>Immunoblotting</B><BR/>Monoclonal Anti-KCNJ10, <B>Cat. No. WH0003766M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37.55 kDa using immunogen protein lysate.
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