Gene Symbol |
KCNT1
|
Entrez Gene |
57582
|
Alt Symbol |
EIEE14, ENFL5, KCa4.1, SLACK, Slo2.2, bA100C15.2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
potassium channel, sodium activated subfamily T, member 1
|
Other Description |
Sequence like a calcium-activated K+ channel|potassium channel subfamily T member 1|potassium channel, subfamily T, member 1
|
Swissprots |
G5E9V0 B9EGP2 B3KXF7 Q9P2C5 Q5JUK3 B7ZVY4
|
Accessions |
EAW88177 EAW88178 EAW88179 EAW88180 EAW88181 EAW88182 Q5JUK3 AB037843 BAA92660 AK123276 AK124588 AK127272 BAG54469 BC136618 AAI36619 BC144304 BC171770 AAI71770 BX110871 DA095802 XM_011518877 XP_011517179 XM_011518878 XP_011517180 XM_011518879 XP_011517181 XM_011518880 XP_011517182 XM_011518881 XP_011517183 NM_001272003 NP_001258932 NM_020822 NP_065873
|
Function |
Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
Tissue Specificity |
Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle. {ECO:0000269|PubMed:10718198}.
|