Gene Symbol | KCNT1 |
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Entrez Gene | 57582 |
Alt Symbol | EIEE14, ENFL5, KCa4.1, SLACK, Slo2.2, bA100C15.2 |
Species | Human |
Gene Type | protein-coding |
Description | potassium channel, sodium activated subfamily T, member 1 |
Other Description | Sequence like a calcium-activated K+ channel|potassium channel subfamily T member 1|potassium channel, subfamily T, member 1 |
Swissprots | G5E9V0 B9EGP2 B3KXF7 Q9P2C5 Q5JUK3 B7ZVY4 |
Accessions | EAW88177 EAW88178 EAW88179 EAW88180 EAW88181 EAW88182 Q5JUK3 AB037843 BAA92660 AK123276 AK124588 AK127272 BAG54469 BC136618 AAI36619 BC144304 BC171770 AAI71770 BX110871 DA095802 XM_011518877 XP_011517179 XM_011518878 XP_011517180 XM_011518879 XP_011517181 XM_011518880 XP_011517182 XM_011518881 XP_011517183 NM_001272003 NP_001258932 NM_020822 NP_065873 |
Function | Outwardly rectifying potassium channel subunit that may coassemble with other Slo-type channel subunits. Activated by high intracellular sodium or chloride levels. Activated upon stimulation of G-protein coupled receptors, such as CHRM1 and GRIA1. May be regulated by calcium in the absence of sodium ions (in vitro) (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
Tissue Specificity | Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle. {ECO:0000269|PubMed:10718198}. |
KCNT1 CRISPR/Cas9 KO Plasmid (h) - sc-412842 from Santa Cruz Biotechnology
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KCNT1 HDR Plasmid (h) - sc-412842-HDR from Santa Cruz Biotechnology
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KCNT1 Double Nickase Plasmid (h) - sc-412842-NIC from Santa Cruz Biotechnology
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KCNT1 Double Nickase Plasmid (h2) - sc-412842-NIC-2 from Santa Cruz Biotechnology
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KCNT1 CRISPR Activation Plasmid (h) - sc-412842-ACT from Santa Cruz Biotechnology
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KCNT1 CRISPR Activation Plasmid (h2) - sc-412842-ACT-2 from Santa Cruz Biotechnology
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KCNT1 Lentiviral Activation Particles (h) - sc-412842-LAC from Santa Cruz Biotechnology
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KCNT1 Lentiviral Activation Particles (h2) - sc-412842-LAC-2 from Santa Cruz Biotechnology
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KCNT1 siRNA (h) - sc-92891 from Santa Cruz Biotechnology
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KCNT1 shRNA Plasmid (h) - sc-92891-SH from Santa Cruz Biotechnology
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KCNT1 shRNA (h) Lentiviral Particles - sc-92891-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU149391 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10994 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10994 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07955 from Sigma-Aldrich
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KCNT1 siRNA (Human) - CRJ1556 from Cohesion Biosciences
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shRNA set against Human KCNT1 (NM_020822.2) - SHH323751 from Creative biogene
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Human KCNT1 siRNA - orb272057 from Biorbyt
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KCNT1 shRNA Plasmid (Human) - CHJ1556 from Cohesion Biosciences
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KCNT1 miRNA 3'UTR clone - MiUTR3H-09806 from Creative biogene
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