| Gene Symbol |
TYW1
|
| Entrez Gene |
55253
|
| Alt Symbol |
RSAFD1, TYW1A, YPL207W
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
|
| Other Description |
S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase|radical S-adenosyl methionine and flavodoxin domain-containing protein 1|radical S-adenosyl methionine and flavodoxin domains 1|tRNA wybutosine-synthesizing protein 1 homolog|tRNA-yW synthesizing protein 1 homolog A
|
| Swissprots |
Q86V12 Q75MN3 Q75MG8 Q9H9C4 Q6PJG8 Q8IVS7 Q9NV66
|
| Accessions |
AAS07520 AAS07568 EAX07903 EAX07904 EAX07905 Q9NV66 AK001762 BAA91891 AK022917 BAB14307 AK301330 BAG62878 BC015591 AAH15591 BC042156 AAH42156 BC051888 AAH51888 XM_011516372 XP_011514674 XM_011516373 XP_011514675 XM_011516374 XP_011514676 XM_011516375 XP_011514677 XR_242254 NM_018264 NP_060734
|
| Function |
Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N- methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). {ECO:0000250}.
|
![Western Blot: TYW1 Overexpression Lysate (Adult Normal) [NBP2-06831] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for TYW1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8228_TYW1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-06831-img0001.jpg)