Gene Symbol | TYW1 |
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Entrez Gene | 55253 |
Alt Symbol | RSAFD1, TYW1A, YPL207W |
Species | Human |
Gene Type | protein-coding |
Description | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) |
Other Description | S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase|radical S-adenosyl methionine and flavodoxin domain-containing protein 1|radical S-adenosyl methionine and flavodoxin domains 1|tRNA wybutosine-synthesizing protein 1 homolog|tRNA-yW synthesizing protein 1 homolog A |
Swissprots | Q86V12 Q75MN3 Q75MG8 Q9H9C4 Q6PJG8 Q8IVS7 Q9NV66 |
Accessions | AAS07520 AAS07568 EAX07903 EAX07904 EAX07905 Q9NV66 AK001762 BAA91891 AK022917 BAB14307 AK301330 BAG62878 BC015591 AAH15591 BC042156 AAH42156 BC051888 AAH51888 XM_011516372 XP_011514674 XM_011516373 XP_011514675 XM_011516374 XP_011514676 XM_011516375 XP_011514677 XR_242254 NM_018264 NP_060734 |
Function | Probable component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Catalyzes the condensation of N- methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine, an intermediate in wybutosine biosynthesis (By similarity). {ECO:0000250}. |
TYW1 CRISPR/Cas9 KO Plasmid (h) - sc-412494 from Santa Cruz Biotechnology
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TYW1 HDR Plasmid (h) - sc-412494-HDR from Santa Cruz Biotechnology
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TYW1 Double Nickase Plasmid (h) - sc-412494-NIC from Santa Cruz Biotechnology
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TYW1 Double Nickase Plasmid (h2) - sc-412494-NIC-2 from Santa Cruz Biotechnology
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TYW1 CRISPR Activation Plasmid (h) - sc-412494-ACT from Santa Cruz Biotechnology
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TYW1 CRISPR Activation Plasmid (h2) - sc-412494-ACT-2 from Santa Cruz Biotechnology
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TYW1 Lentiviral Activation Particles (h) - sc-412494-LAC from Santa Cruz Biotechnology
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TYW1 Lentiviral Activation Particles (h2) - sc-412494-LAC-2 from Santa Cruz Biotechnology
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TYW1 siRNA (h) - sc-89803 from Santa Cruz Biotechnology
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TYW1 shRNA Plasmid (h) - sc-89803-SH from Santa Cruz Biotechnology
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TYW1 shRNA (h) Lentiviral Particles - sc-89803-V from Santa Cruz Biotechnology
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TYW1 RNAi - H00055253-R01 from Novus Biologicals
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MISSION® esiRNA - EHU114241 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN22326 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND22326 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07664 from Sigma-Aldrich
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TYW1 siRNA (Human) - CRJ0598 from Cohesion Biosciences
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TYW1 - MBS828603 from MyBioSource
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shRNA set against Human TYW1(NM_018264.2) - SHL109036 from Creative biogene
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TYW1 shRNA Plasmid (Human) - CHJ0598 from Cohesion Biosciences
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TYW1 miRNA 3'UTR clone - MiUTR1H-10911 from Creative biogene
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