CEP290

Gene Symbol	CEP290
Entrez Gene	80184
Alt Symbol	3H11Ag, BBS14, CT87, JBTS5, LCA10, MKS4, NPHP6, POC3, SLSN6, rd16
Species	Human
Gene Type	protein-coding
Description	centrosomal protein 290kDa
Other Description	Bardet-Biedl syndrome 14 protein|CTCL tumor antigen se2-2|Meckel syndrome, type 4|POC3 centriolar protein homolog|cancer/testis antigen 87|centrosomal protein of 290 kDa|monoclonal antibody 3H11 antigen|nephrocytsin-6|prostate cancer antigen T21|tumor antigen se2-2
Swissprots	Q9H6Q7 Q66GS8 Q1PSK5 Q9H8I0 Q9H2G6 O15078
Accessions	EAW97413 EAW97414 O15078 AB002371 BAA20828 AF273044 AAG34904 AF317887 AAK01919 AK023677 AK025632 BAB15196 AY590151 AAT01278 BC008641 AAH08641 BC043398 AAH43398 BC156462 AAI56463 BC172566 AAI72566 BK005587 DAA05591 BU676074 DQ109808 AAZ83370 XM_011538756 XP_011537058 XM_011538757 XP_011537059 XM_011538758 XP_011537060 XM_011538759 XP_011537061 XM_011538760 XP_011537062 XM_011538761 XP_011537063 XM_011538762 XP_011537064 XM_011538763 XP_011537065 XM_011538764 XP_011537066 XM_011538765 XP_011537067 XM_011538766 XP_011537068 NM_025114 NP_079390
Function	Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes. {ECO:0000250|UniProtKB:Q6A078, ECO:0000269|PubMed:16682973}.
Subcellular Location	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite. Nucleus. Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250}. Note=Connecting cilium of photoreceptor cells, base of cilium in kidney intramedullary collecting duct cells. Localizes at the transition zone, a region between the basal body and the ciliary axoneme (By similarity). Displaced from centriolar satellites in response to cellular stress, such as ultraviolet light (UV) radiation or heat shock. {ECO:0000250}.
Tissue Specificity	Ubiquitous. Expressed strongly in placenta and weakly in brain. {ECO:0000269|PubMed:11149944, ECO:0000269|PubMed:16682973}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human CEP290 protein fragment - ab164215 from Abcam Category Protein Source Wheat germ Species Human

CEP290 Antibody Blocking Peptide - LS-E26641 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CEP290 Antibody Blocking Peptide - LS-E26961 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human CEP290 Protein - H00080184-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

CEP290 blocking peptide - GTX88258-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse

CEP290 blocking peptide - GTX88808-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Goat anti CEP290 antibody Immunizing peptide - orb15083 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

Goat anti CEP290 antibody Immunizing peptide - orb50344 from Biorbyt Category Peptide Prices $247.00 Sizes 100 μg Species Human, Mouse, Rat

CEP290 Blocking Peptide - abx063986 from Abbexa Category Peptide Species Human, Bovine

CEP290 Peptide - AC21-1477-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CEP290 Peptide - AC21-1789-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

CEP290 - H00080184-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CEP290 - H00080184-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

CEP290 Peptide - 46-639P from ProSci Category Peptide

CEP290 Peptide - 42-225P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

CEP290 fusion protein - Ag17457 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

CEP290 fusion protein - ag16887 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CEP290, His-tagged - CEP290-11112H from Creative Biomart Category Protein Source E.coli Species Human

CEP290 Blocking Peptide - CBP2792 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Bovine

CEP290 (F812) Peptide - BS3831P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Centrosomal protein of 290 kDa(CEP290) ,partial - CSB-YP005241HU CSB-EP005241HU CSB-BP005241HU CSB-MP005241HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Centrosomal protein of 290 kDa (CEP290), partial, Recombinant Protein - MBS1048599 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

CEP290, Peptide - MBS659811 from MyBioSource Category Peptide Prices $340.00 Sizes 100 µg

CEP290 , Peptide - MBS425126 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

CEP290/NPHP6, Peptide - MBS428360 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

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