ACER3

Gene Symbol ACER3
Entrez Gene 55331
Alt Symbol APHC, PHCA
Species Human
Gene Type protein-coding
Description alkaline ceramidase 3
Other Description alkCDase 3|alkaline CDase 3|alkaline dihydroceramidase SB89|alkaline phytoceramidase|phytoceramidase, alkaline
Swissprots B2RC99 Q9NUN7
Accessions EAW75009 EAW75010 EAW75011 EAW75012 Q9NUN7 AF214454 AAK71923 AF327353 AAL56013 AI885537 AK002100 BAA92085 AK293800 BAH11598 AK294978 BAH11938 AK295142 BAH11988 AK295327 BAH12032 AK308856 AK315000 BAG37496 AK316120 BAH14491 BC049837 BC063034 BC073853 AAH73853 BG702017 DB461413 HQ447508 ADQ31994 XM_005274087 XP_005274144 XM_005274092 XP_005274149 XM_011545151 XP_011543453 XM_011545152 XP_011543454 XM_011545153 XP_011543455 XM_011545154 XP_011543456 XR_949982 XR_949983 XR_949984 XR_949985 NM_001300953 NP_001287882 NM_001300954 NP_001287883 NM_001300955 NP_001287884 NM_018367 NP_060837
Function Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
Subcellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
Tissue Specificity Ubiquitously expressed. Highest expression in placenta.
Top Pathways Sphingolipid metabolism

APHC (K-13) - sc-241829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APHC (N-15) - sc-241828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Phytoceramidase antibody - ab196760 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Phytoceramidase antibody (ab196760) at 1/500 dilutionLane 1 : COLO cell extractsLane 2 : COLO cell extracts with blocking peptide

Anti-Phytoceramidase antibody - ab101023 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-Phytoceramidase antibody (ab101023) at 1/500 dilution + Human fetal brain Lysate

Anti-Phytoceramidase antibody - ab137896 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Phytoceramidase antibody (ab137896) at 1/500 dilution + HT29 cell lysate at 30 µg

Anti-Phytoceramidase antibody - C-terminal - ab135836 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometry analysis of HepG2 cells labelling Phytoceramidase with ab135836 at 1/10 dilution (right histogram) compared to negative control celsl (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Anti-ACER3 Antibody (C-Terminus, APC) - LS-C275141 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus, FITC) - LS-C275144 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus, AP) - LS-C275139 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus, Azide-free, HRP) - LS-C275145 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus, Biotin) - LS-C275143 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus) - LS-C326851 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (C-Terminus, PE) - LS-C275146 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-ACER3 Antibody (aa160-209) - LS-C200485 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HT-29 cells using PHCA antibody.

Anti-ACER3 Antibody (aa224-250) - LS-C155927 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of ACER3 Antibody in HepG2 cell line lysates (35 ug/lane). ACER3 (arrow) was detected using the purified antibody.

Anti-ACER3 Antibody (aa171-220) - LS-C119713 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human placenta tissue, using PHCA Antibody. The picture on the right is treated with the synthesized peptide.

PHCA Antibody - NBP1-71578 from Novus Biologicals

Prices $229.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PHCA Antibody [NBP1-71578] - Analysis of extracts from COLO cells, using PHCA Antibody. The lane on the right is treated with the synthesized peptide.

ANTI-ACER3 (C-TERM) antibody produced in rabbit - SAB1303797 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-ACER3 (C-term): <B>Cat. No. SAB1303797</B>: Western blot analysis of ACER3 Antibody (C-term) in HepG2 cell line lysates (35 μg/lane).

Anti-PHCA antibody produced in rabbit - SAB4502315 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PHCA: <B>Cat. No. SAB4502315</B>: Immunohistochemistry analysis of paraffin-embedded human placenta tissue using Anti-PHCA antibody. Cells on the left were treated with the Anti-PHCA antibody. Cells on the right (negative control) were treated with both Anti-PHCA antibody and the synthesized immunogen peptide.

ACER3-Antibody-C-term - AP8953b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of ACER3 Antibody (C-term) (Cat. #AP8953b) in HepG2 cell line lysates (35ug/lane). ACER3 (arrow) was detected using the purified Pab.

ACER3 antibody, C-term - GTX80919 from GeneTex

Prices $319.00
Sizes 400 μl
Host Rabbit
Clonality Polyclonal
Anti-ACER3 antibody, C-term used in Flow cytometry/FACS. GTX80919

ACER3 Antibody - C-terminal region (OAAB05549) - OAAB05549 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

ACER3 Antibody (OAAF03261) - OAAF03261 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PHCA Antibody (OAAF06931) - OAAF06931 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

ACER3 antibody - orb77489 from Biorbyt

Prices $425.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of fetal brain lysate using ACER3 antibody
Search more