| Gene Symbol |
ACER3
|
| Entrez Gene |
55331
|
| Alt Symbol |
APHC, PHCA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
alkaline ceramidase 3
|
| Other Description |
alkCDase 3|alkaline CDase 3|alkaline dihydroceramidase SB89|alkaline phytoceramidase|phytoceramidase, alkaline
|
| Swissprots |
B2RC99 Q9NUN7
|
| Accessions |
EAW75009 EAW75010 EAW75011 EAW75012 Q9NUN7 AF214454 AAK71923 AF327353 AAL56013 AI885537 AK002100 BAA92085 AK293800 BAH11598 AK294978 BAH11938 AK295142 BAH11988 AK295327 BAH12032 AK308856 AK315000 BAG37496 AK316120 BAH14491 BC049837 BC063034 BC073853 AAH73853 BG702017 DB461413 HQ447508 ADQ31994 XM_005274087 XP_005274144 XM_005274092 XP_005274149 XM_011545151 XP_011543453 XM_011545152 XP_011543454 XM_011545153 XP_011543455 XM_011545154 XP_011543456 XR_949982 XR_949983 XR_949984 XR_949985 NM_001300953 NP_001287882 NM_001300954 NP_001287883 NM_001300955 NP_001287884 NM_018367 NP_060837
|
| Function |
Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Ubiquitously expressed. Highest expression in placenta.
|
| Top Pathways |
Sphingolipid metabolism
|