| Gene Symbol |
CERS2
|
| Entrez Gene |
29956
|
| Alt Symbol |
L3, LASS2, SP260, TMSG1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ceramide synthase 2
|
| Other Description |
LAG1 homolog, ceramide synthase 2|LAG1 longevity assurance 2|longevity assurance (LAG1, S. cerevisiae) homolog 2|tumor metastasis-suppressor gene 1 protein
|
| Swissprots |
D3DV06 Q9HD96 Q96G23 Q9NW79 Q5SZE5
|
| Accessions |
CAC33275 EAW53497 EAW53498 EAW53499 EAW53500 EAW53501 EAW53502 Q96G23 AF177338 AAG17982 AF189062 AAF01058 AK001105 BAA91505 AK290989 BAF83678 AY091458 AAM12028 BC001357 AAH01357 BC010032 AAH10032 BM069521 BM764143 BQ219926 BU543940 DA019883 EU446492 ABZ92021 R94703 XM_005245107 XP_005245164 XM_011509451 XP_011507753 XM_011509452 XP_011507754 NM_022075 NP_071358 NM_181746 NP_859530 NM_013384
|
| Function |
Suppresses the growth of cancer cells. May be involved in sphingolipid synthesis.
|
| Subcellular Location |
Nucleus membrane {ECO:0000255|PROSITE- ProRule:PRU00108}; Multi-pass membrane protein {ECO:0000305}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
|
| Tissue Specificity |
Expressed in kidney, liver, brain, heart, placenta and lung. {ECO:0000269|PubMed:11543633}.
|
| Top Pathways |
Sphingolipid signaling pathway, Sphingolipid metabolism
|