| Gene Symbol |
SI
|
| Entrez Gene |
6476
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
sucrase-isomaltase (alpha-glucosidase)
|
| Other Description |
oligosaccharide alpha-1,6-glucosidase|sucrase-isomaltase, intestinal
|
| Swissprots |
Q1RMC2 P14410 A2RUC3 Q1JQ80
|
| Accessions |
EAW78601 P14410 AA376756 BC115033 BC115034 AAI15035 BC116452 AAI16453 BC116453 BC132834 AAI32835 BC132860 AAI32861 BG187733 DA919374 M22616 AAA60551 X63597 CAA45140 XM_011513078 XP_011511380 NM_001041 NP_001032
|
| Function |
Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides. {ECO:0000269|PubMed:20356844}.
|
| Subcellular Location |
Apical cell membrane; Single-pass type II membrane protein. Note=Brush border.
|
| Tissue Specificity |
Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon. {ECO:0000269|PubMed:1677636}.
|
| Top Pathways |
Carbohydrate digestion and absorption, Galactose metabolism, Starch and sucrose metabolism
|