Gene Symbol | SI |
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Entrez Gene | 6476 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | sucrase-isomaltase (alpha-glucosidase) |
Other Description | oligosaccharide alpha-1,6-glucosidase|sucrase-isomaltase, intestinal |
Swissprots | Q1RMC2 P14410 A2RUC3 Q1JQ80 |
Accessions | EAW78601 P14410 AA376756 BC115033 BC115034 AAI15035 BC116452 AAI16453 BC116453 BC132834 AAI32835 BC132860 AAI32861 BG187733 DA919374 M22616 AAA60551 X63597 CAA45140 XM_011513078 XP_011511380 NM_001041 NP_001032 |
Function | Plays an important role in the final stage of carbohydrate digestion. Isomaltase activity is specific for both alpha-1,4- and alpha-1,6-oligosaccharides. {ECO:0000269|PubMed:20356844}. |
Subcellular Location | Apical cell membrane; Single-pass type II membrane protein. Note=Brush border. |
Tissue Specificity | Expressed in the poorly differentiated crypt cells of the small intestine as well as in the mature villous cells. Expressed at very low levels in the colon. {ECO:0000269|PubMed:1677636}. |
Top Pathways | Carbohydrate digestion and absorption, Galactose metabolism, Starch and sucrose metabolism |
Sucrase-Isomaltase (A-12) - sc-393424 from Santa Cruz Biotechnology
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Sucrase-Isomaltase (C-8) - sc-393470 from Santa Cruz Biotechnology
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Sucrase-Isomaltase (A-17) - sc-27603 from Santa Cruz Biotechnology
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Sucrase-Isomaltase (L-20) - sc-27608 from Santa Cruz Biotechnology
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Sucrase-Isomaltase (T-17) - sc-27611 from Santa Cruz Biotechnology
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Sucrase-Isomaltase (D-20) - sc-27605 from Santa Cruz Biotechnology
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Anti-SI antibody - ab84977 from Abcam
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Anti-SI antibody - ab55738 from Abcam
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Anti-SI antibody - ab98872 from Abcam
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Anti-SI antibody [4B92.1] - ab105471 from Abcam
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Anti-SI antibody [4C5G6] - ab105467 from Abcam
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Anti-SI / Sucrase Isomaltase Antibody (Biotin) - LS-C147436 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody - LS-C147435 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody - LS-C147437 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (aa1717-1827, Biotin) - LS-C300877 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (aa1717-1827, FITC) - LS-C304474 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (aa1691-1740) - LS-C107948 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (aa144-193) - LS-C102144 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (clone 1A8) - LS-C198193 from LifeSpan Bioscience
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Anti-SI / Sucrase Isomaltase Antibody (aa1717-1827) - LS-C296520 from LifeSpan Bioscience
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SI Sucrase-Isomaltase Antibody - NBP1-87581 from Novus Biologicals
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SI Sucrase-Isomaltase Antibody - NBP1-69357 from Novus Biologicals
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SI Sucrase-Isomaltase Antibody - NBP1-69385 from Novus Biologicals
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SI Sucrase-Isomaltase Antibody (1A8) - H00006476-M01 from Novus Biologicals
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SI Sucrase-Isomaltase Antibody - H00006476-A01 from Novus Biologicals
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