TEX14

Gene Symbol	TEX14
Entrez Gene	56155
Alt Symbol	CT113
Species	Human
Gene Type	protein-coding
Description	testis expressed 14
Other Description	cancer/testis antigen 113|inactive serine/threonine-protein kinase TEX14|protein kinase-like protein SgK307|sugen kinase 307|testis expressed sequence 14|testis-expressed protein 14|testis-expressed sequence 14 protein
Swissprots	Q9BXT9 Q8IWB6 Q8ND97 A6NH19 Q7RTP3
Accessions	EAW94437 EAW94438 Q8IWB6 AF285601 AAK31980 AI243203 AK125896 AK128217 AK308299 AL834143 CAD38856 BC040526 AAH40526 BC045647 BG718877 BK000998 DAA01359 CB044007 CB050840 DB086121 GQ129421 ACT64555 XM_011525028 XP_011523330 XM_011525029 XP_011523331 XM_011525030 XP_011523332 XM_011525031 XP_011523333 XM_011525032 XP_011523334 XM_011525033 XP_011523335 NM_001201457 NP_001188386 NM_031272 NP_112562 NM_198393 NP_938207
Function	Required both for the formation of intercellular bridges during meiosis and for kinetochore-microtubule attachment during mitosis. Intercellular bridges are evolutionarily conserved structures that connect differentiating germ cells and are required for spermatogenesis and male fertility. Acts by promoting the conversion of midbodies into intercellular bridges via its interaction with CEP55: interaction with CEP55 inhibits the interaction between CEP55 and PDCD6IP/ALIX and TSG101, blocking cell abscission and leading to transform midbodies into intercellular bridges. Also plays a role during mitosis: recruited to kinetochores by PLK1 during early mitosis and regulates the maturation of the outer kinetochores and microtubule attachment. Has no protein kinase activity in vitro (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}. Midbody {ECO:0000250}. Chromosome, centromere, kinetochore {ECO:0000250}. Note=Detected in the intercellular bridges that connect male germ cell daughter cells after cell division. {ECO:0000250}.
Tissue Specificity	Detected in testis. {ECO:0000269|PubMed:11279525}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tex14 peptide - ab42413 from Abcam Category Peptide

Human Tex14 protein fragment - ab163350 from Abcam Category Protein Source Wheat germ Species Human

Mouse Tex14 peptide - ab42412 from Abcam Category Peptide

TEX14 Antibody Blocking Peptide - LS-E19507 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TEX14 Antibody Blocking Peptide - LS-E19508 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Tex14 Protein - H00056155-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

TEX14 Blocking Peptide - 33R-1529 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TEX14 Blocking Peptide - 33R-9217 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

TEX14 - H00056155-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

TEX14 - H00056155-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TEX14 fusion protein - Ag13177 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

TEX14 fusion protein - ag13143 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human TEX14, GST-tagged - TEX14-3190H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Inactive serine/threonine-protein kinase TEX14(TEX14) ,partial - CSB-YP815562HU CSB-EP815562HU CSB-BP815562HU CSB-MP815562HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

TEX14 Peptide, Human - M34GP15813H from Creative Peptides Category Peptide Source Synthetic. Species Human

Inactive serine/threonine-protein kinase TEX14 (TEX14), partial, Recombinant Protein - MBS1392010 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more