Foxi1
| Gene Symbol | Foxi1 |
|---|---|
| Entrez Gene | 14233 |
| Alt Symbol | 5830401E05Rik, FREAC6, Fkh10, HFH-3, Hfh3 |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | forkhead box I1 |
| Other Description | HNF-3/forkhead homolog 3|forkhead box protein I1|forkhead homolog 10 |
| Swissprots | Q5SRI5 Q922I5 Q9D299 |
| Accessions | AAD05558 EDL23726 EDL23727 Q922I5 AK019994 BAB31957 BC007475 AAH07475 BF454473 NM_023907 NP_076396 |
| Function | Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules. {ECO:0000269|PubMed:12642503, ECO:0000269|PubMed:15173882}. |
| Subcellular Location | Nucleus. |
| Tissue Specificity | Expressed in intercalated cells of the epithelium of the distal renal tubule. {ECO:0000269|PubMed:15173882}. |
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