| Gene Symbol |
Foxi1
|
| Entrez Gene |
14233
|
| Alt Symbol |
5830401E05Rik, FREAC6, Fkh10, HFH-3, Hfh3
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
forkhead box I1
|
| Other Description |
HNF-3/forkhead homolog 3|forkhead box protein I1|forkhead homolog 10
|
| Swissprots |
Q5SRI5 Q922I5 Q9D299
|
| Accessions |
AAD05558 EDL23726 EDL23727 Q922I5 AK019994 BAB31957 BC007475 AAH07475 BF454473 NM_023907 NP_076396
|
| Function |
Transcriptional activator required for the development of normal hearing, sense of balance and kidney function. Required for the expression of SLC26A4/PDS, JAG1 and COCH in a subset of epithelial cells and the development of the endolymphatic system in the inner ear. Also required for the expression of SLC4A1/AE1, SLC4A9/AE4, ATP6V1B1 and the differentiation of intercalated cells in the epithelium of distal renal tubules. {ECO:0000269|PubMed:12642503, ECO:0000269|PubMed:15173882}.
|
| Subcellular Location |
Nucleus.
|
| Tissue Specificity |
Expressed in intercalated cells of the epithelium of the distal renal tubule. {ECO:0000269|PubMed:15173882}.
|