| Gene Symbol |
CYP2C18
|
| Entrez Gene |
1562
|
| Alt Symbol |
CPCI, CYP2C, CYP2C17, P450-6B/29C, P450IIC17
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cytochrome P450, family 2, subfamily C, polypeptide 18
|
| Other Description |
(S)-mephenytoin hydroxylase associated cytochrome P450|CYPIIC18|cytochrome P450 2C18|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 17|cytochrome P450, subfamily IIC (mephenytoin 4-hydroxylase), polypeptide 18|cytochrome P450-6B/29C|flavoprotein-linked monooxygenase|microsomal monooxygenase|unspecific monooxygenase
|
| Swissprots |
P33260 Q4VAT5 Q6GRG1 Q16751 Q16703 B2R8K2
|
| Accessions |
AAA02630 CAA39833 EAW50024 P33260 AK223510 BAD97230 AK308558 AK313403 BAG36199 BC069666 AAH69666 BC096257 AAH96257 BC096258 AAH96258 BC096259 BC096260 AAH96260 BJ993698 BX538127 CAD98029 HQ447473 ADQ31959 M61853 M61856 AAB59356 NM_000772 NP_000763 NM_001128925 NP_001122397
|
| Function |
Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
|
| Subcellular Location |
Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
|
| Top Pathways |
Chemical carcinogenesis, Retinol metabolism
|