Gene Symbol |
ORC1
|
Entrez Gene |
4998
|
Alt Symbol |
HSORC1, ORC1L, PARC1
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
origin recognition complex, subunit 1
|
Other Description |
origin recognition complex subunit 1|origin recognition complex, subunit 1 homolog|replication control protein 1
|
Swissprots |
Q5T0F5 D3DQ34 Q13415 Q13471
|
Accessions |
EAX06783 EAX06784 Q13415 AK291909 BAF84598 AK303420 BAH13956 BC011539 AAH11539 BP280383 DB156841 U40152 AAC50325 U43416 AAA86260 XM_011541527 XP_011539829 NM_001190818 NP_001177747 NM_001190819 NP_001177748 NM_004153 NP_004144
|
Function |
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.
|
Subcellular Location |
Nucleus.
|
Top Pathways |
Cell cycle
|