VIPR1

Gene Symbol VIPR1
Entrez Gene 7433
Alt Symbol HVR1, II, PACAP-R-2, PACAP-R2, RDC1, V1RG, VAPC1, VIP-R-1, VIPR, VIRG, VPAC1, VPAC1R, VPCAP1R
Species Human
Gene Type protein-coding
Description vasoactive intestinal peptide receptor 1
Other Description PACAP type II receptor|VIP and PACAP receptor 1|VIP receptor, type I|pituitary adenylate cyclase activating polypeptide receptor, type II|vasoactive intestinal polypeptide receptor 1
Swissprots F5H1F5 P32241 Q6P2M6 A5JUT9 G3V0I1 B4DEB5 B3KPV1 B4DGI4 Q15871
Accessions AAB60362 BAC05895 CAS01788 EAW64649 EAW64650 EAW64651 EAW64652 P32241 AK056819 BAG51813 AK123943 AK126759 AK293548 BAG57026 AK294609 BAG57795 AK298115 BAG60398 AK314334 BAG36980 BC064424 AAH64424 BU681817 DA200439 EF577396 ABQ52416 L13288 AAA36805 L20295 AAA36802 X75299 CAA53046 XM_005265437 XP_005265494 XM_005265438 XP_005265495 XM_005265439 XP_005265496 XM_011534079 XP_011532381 XM_011534080 XP_011532382 XR_940499 XR_940500 NM_001251882 NP_001238811 NM_001251883 NP_001238812 NM_001251884 NP_001238813 NM_001251885 NP_001238814 NM_004624 NP_004615
Function This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. {ECO:0000269|PubMed:8926282}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T- cell lines Peer, MOLT-4, HSB and YT. {ECO:0000269|PubMed:8926282}.
Top Pathways Neuroactive ligand-receptor interaction

VPAC1 (B-4) - sc-377152 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VPAC1 (B-4): sc-377152. Western blot analysis of VPAC1 expression in non-transfected: sc-117752 (A) and human VPAC1 transfected: sc-116969 (B) and 293T whole cell lysates.

VPAC1 (K-19) - sc-31634 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

VPAC1 (V-20) - sc-31633 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPAC1 (V-20): sc-31633. Western blot analysis of VPAC1 expression in non-transfected: sc-117752 (A) and human VPAC1 transfected: sc-116969 (B) 293T whole cell lysates.

VPAC1 (H-130) - sc-30019 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
VPAC1 (H-130): sc-30019. Western blot analysis of VPAC1 expression in TE671 (A), SK-N-SH (B) and Caki-1 (C) whole cell lysates.

VPAC1 (N-15) - sc-15958 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-VIP Receptor 1 antibody - ab106244 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIP Receptor 1 antibody - ab139746 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VIP Receptor 1 antibody (ab139746) at 1 µg/ml + Lung (Human) Tissue Lysate (ab4014) at 30 µgSecondaryGoat Anti-Rabbit IgG H&L (HRP) (ab97051) at 1/10000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-VIP Receptor 1 antibody - ab181799 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human lung tissue, staining VIP Receptor 1 with ab181799 at 1/50 dilution.

Anti-VIP Receptor 1 antibody - ab138260 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VIP Receptor 1 antibody (ab138260) at 1/500 dilution + HeLa cell lysate at 30 µg

Anti-VIP Receptor 1 antibody [AS58] - ab16155 from Abcam

Host Mouse
Clonality Monoclonal
Clone AS58
Anti-VIP Receptor 1 antibody [AS58] (ab16155) at 1 µg/ml + HT29 (Human colon adenocarcinoma grade II cell line) Whole Cell Lysate (ab3952) at 10 µg/mlSecondaryGoat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-VIP Receptor 1 antibody [SP234] - ab183312 from Abcam

Host Rabbit
Clonality Monoclonal
Clone SP234
Immunohistochemical analysis of Human tonsil tissue labeling VIP Receptor 1 using ab183312 at a 1/100 dilution

Anti-VIPR1 antibody - ab172251 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-VIPR1 antibody (ab172251) at 1 µg/mlLane 1 : VIPR1-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG (H+L)-HRP at 1/2500 dilutiondeveloped using the ECL technique

Anti-VIPR1 Antibody (N-Terminus) - LS-C40146 from LifeSpan Bioscience

Prices $415.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (aa91-104) - LS-C154859 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-VIPR1 Antibody (aa305-334, AP) - LS-C218420 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (aa305-334, APC) - LS-C218421 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (aa305-334, FITC) - LS-C218422 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (aa322-371) - LS-C200815 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from HeLa cells using VIPR1 antibody.

Anti-VIPR1 Antibody (aa305-334, Biotin) - LS-C218423 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody - LS-C27045 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot of anti-VIPR1 antibody on A431 cell lysate at 1 ug/ml (1) and 10 ug/ml (2).

Anti-VIPR1 Antibody (aa305-334, Azide-free, HRP) - LS-C218424 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (Val371) - LS-C177415 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of VPAC1 (V371) pAb in extracts from HT-29 cells.

Anti-VIPR1 Antibody (aa305-334, PE) - LS-C218425 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VIPR1 Antibody (Cytoplasmic Domain) IHC-plus™ - LS-A1297 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-VIP Receptor 1 antibody LS-A1297 IHC of human adipocytes. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Anti-VIPR1 Antibody (aa332-381) - LS-C120970 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of MCF7 cells, using VIPR1 Antibody. The picture on the right is treated with the synthesized peptide.
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