| Gene Symbol |
EPT1
|
| Entrez Gene |
85465
|
| Alt Symbol |
SELI, SEPI
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
ethanolaminephosphotransferase 1
|
| Other Description |
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)|hEPT1|selenoprotein I
|
| Swissprots |
Q63ZE3 Q9C0D9
|
| Accessions |
AAY14646 EAX00690 EAX00691 EAX00692 EAX00693 Q9C0D9 AB051511 BAB21815 AB621826 BAK64161 AK023242 AK091340 AK092710 AK095620 BC015430 BC021229 AAH21229 BE963795 BF669898 BK001426 DAA01514 DA619246 DA905145 EH350337 NM_033505 NP_277040
|
| Function |
Catalyzes phosphatidylethanolamine biosynthesis from CDP-ethanolamine. It thereby plays a central role in the formation and maintenance of vesicular membranes. Involved in the formation of phosphatidylethanolamine via 'Kennedy' pathway.
|
| Subcellular Location |
Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
|
| Tissue Specificity |
Widely expressed. Abundant in brain, placenta, liver and pancreas, followed by heart, skeletal muscle, lung and kidney. In brain it is strongly expressed in cerebellum, followed by the occipital pole and the frontal lobe. {ECO:0000269|PubMed:17132865}.
|
| Top Pathways |
Ether lipid metabolism, Glycerophospholipid metabolism
|
![Western Blot: SELI Antibody [H00085465-A01] - Analysis of SELI expression in HeLa (Cat # L013V1).](http://www.bioprodhub.com/system/product_images/ab_products/5/sub_10/9435_SELI%2520Antibody-Western%2520Blot-H00085465-A01-img0002.jpg)
