| Gene Symbol |
HBP1
|
| Entrez Gene |
26959
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
HMG-box transcription factor 1
|
| Other Description |
HMG box transcription factor 1|HMG box-containing protein 1|high mobility group box transcription factor 1
|
| Swissprots |
Q8TE93 Q96AJ2 Q8TBM1 B3KVB7 O60381
|
| Accessions |
AAC08317 EAW83392 EAW83393 EAW83394 O60381 AF019214 AAB71862 AF182038 AAD56225 AK025284 AK074353 BAB85059 AK122785 BAG53729 AK295910 BAG58698 AK298504 BAG60711 BC017069 AAH17069 BC022329 AAH22329 DQ891576 ABM82502 XM_005250266 XP_005250323 XM_005250267 XP_005250324 XR_927445 NM_001244262 NP_001231191 NM_012257 NP_036389
|
| Function |
Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. {ECO:0000269|PubMed:10562551, ECO:0000269|PubMed:10958660, ECO:0000269|PubMed:11500377}.
|
| Subcellular Location |
Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:10562551}.
|
