Gene Symbol | HBP1 |
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Entrez Gene | 26959 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | HMG-box transcription factor 1 |
Other Description | HMG box transcription factor 1|HMG box-containing protein 1|high mobility group box transcription factor 1 |
Swissprots | Q8TE93 Q96AJ2 Q8TBM1 B3KVB7 O60381 |
Accessions | AAC08317 EAW83392 EAW83393 EAW83394 O60381 AF019214 AAB71862 AF182038 AAD56225 AK025284 AK074353 BAB85059 AK122785 BAG53729 AK295910 BAG58698 AK298504 BAG60711 BC017069 AAH17069 BC022329 AAH22329 DQ891576 ABM82502 XM_005250266 XP_005250323 XM_005250267 XP_005250324 XR_927445 NM_001244262 NP_001231191 NM_012257 NP_036389 |
Function | Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. {ECO:0000269|PubMed:10562551, ECO:0000269|PubMed:10958660, ECO:0000269|PubMed:11500377}. |
Subcellular Location | Nucleus {ECO:0000255|PROSITE- ProRule:PRU00267, ECO:0000269|PubMed:10562551}. |
HBP1 CRISPR/Cas9 KO Plasmid (h) - sc-418420 from Santa Cruz Biotechnology
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HBP1 HDR Plasmid (h) - sc-418420-HDR from Santa Cruz Biotechnology
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HBP1 Double Nickase Plasmid (h) - sc-418420-NIC from Santa Cruz Biotechnology
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HBP1 Double Nickase Plasmid (h2) - sc-418420-NIC-2 from Santa Cruz Biotechnology
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HBP1 CRISPR Activation Plasmid (h) - sc-418420-ACT from Santa Cruz Biotechnology
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HBP1 CRISPR Activation Plasmid (h2) - sc-418420-ACT-2 from Santa Cruz Biotechnology
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HBP1 Lentiviral Activation Particles (h) - sc-418420-LAC from Santa Cruz Biotechnology
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HBP1 Lentiviral Activation Particles (h2) - sc-418420-LAC-2 from Santa Cruz Biotechnology
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HBP1 siRNA (h) - sc-35532 from Santa Cruz Biotechnology
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HBP1 shRNA Plasmid (h) - sc-35532-SH from Santa Cruz Biotechnology
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HBP1 shRNA (h) Lentiviral Particles - sc-35532-V from Santa Cruz Biotechnology
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HBP1 RNAi - H00026959-R01 from Novus Biologicals
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MISSION® esiRNA - EHU131981 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9905 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9905 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07750 from Sigma-Aldrich
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HBP1 siRNA (Human) - CRH8904 from Cohesion Biosciences
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HBP1 - MBS8231950 from MyBioSource
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shRNA set against Human HBP1 (NM_012257.3) - SHH310645 from Creative biogene
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Human HBP1 siRNA - orb269406 from Biorbyt
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HBP1 shRNA Plasmid (Human) - CHH8904 from Cohesion Biosciences
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HBP1 miRNA 3'UTR clone - MiUTR1H-04391 from Creative biogene
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