Gene Symbol |
TAS2R13
|
Entrez Gene |
50838
|
Alt Symbol |
T2R13, TRB3
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
taste receptor, type 2, member 13
|
Other Description |
taste receptor family B member 3|taste receptor type 2 member 13|taste receptor, family B, member 3
|
Swissprots |
Q4G0I5 Q645X2 Q502V8 Q9NYV9
|
Accessions |
AAF43910 BAD97991 BAD97992 BAD97993 CAI53559 EAW96218 Q9NYV9 BC069376 AAH69376 BC095518 AAH95518 BC115402 AAI15403 BC115403 HQ448415 ADQ32895 NM_023920 NP_076409
|
Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
|
Subcellular Location |
Membrane; Multi-pass membrane protein.
|
Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.
|
Top Pathways |
Taste transduction
|