Gene Symbol | TAS2R13 |
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Entrez Gene | 50838 |
Alt Symbol | T2R13, TRB3 |
Species | Human |
Gene Type | protein-coding |
Description | taste receptor, type 2, member 13 |
Other Description | taste receptor family B member 3|taste receptor type 2 member 13|taste receptor, family B, member 3 |
Swissprots | Q4G0I5 Q645X2 Q502V8 Q9NYV9 |
Accessions | AAF43910 BAD97991 BAD97992 BAD97993 CAI53559 EAW96218 Q9NYV9 BC069376 AAH69376 BC095518 AAH95518 BC115402 AAI15403 BC115403 HQ448415 ADQ32895 NM_023920 NP_076409 |
Function | Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells. |
Top Pathways | Taste transduction |
T2R13 CRISPR/Cas9 KO Plasmid (h) - sc-418436 from Santa Cruz Biotechnology
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T2R13 HDR Plasmid (h) - sc-418436-HDR from Santa Cruz Biotechnology
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T2R13 Double Nickase Plasmid (h) - sc-418436-NIC from Santa Cruz Biotechnology
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T2R13 Double Nickase Plasmid (h2) - sc-418436-NIC-2 from Santa Cruz Biotechnology
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T2R13 CRISPR Activation Plasmid (h) - sc-418436-ACT from Santa Cruz Biotechnology
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T2R13 CRISPR Activation Plasmid (h2) - sc-418436-ACT-2 from Santa Cruz Biotechnology
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T2R13 Lentiviral Activation Particles (h) - sc-418436-LAC from Santa Cruz Biotechnology
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T2R13 Lentiviral Activation Particles (h2) - sc-418436-LAC-2 from Santa Cruz Biotechnology
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T2R13 siRNA (h) - sc-96215 from Santa Cruz Biotechnology
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T2R13 shRNA Plasmid (h) - sc-96215-SH from Santa Cruz Biotechnology
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T2R13 shRNA (h) Lentiviral Particles - sc-96215-V from Santa Cruz Biotechnology
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TAS2R13 RNAi - H00050838-R02 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN21014 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21014 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03968 from Sigma-Aldrich
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TAS2R13 siRNA (Human) - CRH9419 from Cohesion Biosciences
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TAS2R13 - MBS8202118 from MyBioSource
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shRNA set against Human TAS2R13 (NM_023920.2) - SHH423400 from Creative biogene
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shRNA set against Human TAS2R13(NM_023920.2) - SHL057294 from Creative biogene
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Human TAS2R13 siRNA - orb269921 from Biorbyt
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TAS2R13 shRNA Plasmid (Human) - CHH9419 from Cohesion Biosciences
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TAS2R13 miRNA 3'UTR clone - MiUTR1H-10192 from Creative biogene
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