| Gene Symbol | ZNF431 |
|---|---|
| Entrez Gene | 170959 |
| Alt Symbol | - |
| Species | Human |
| Gene Type | protein-coding |
| Description | zinc finger protein 431 |
| Other Description | - |
| Swissprots | Q8TF32 Q8IWC4 A8KAK7 |
| Accessions | EAW84888 EAW84889 EAW84890 Q8TF32 AB075849 BAB85555 AK021615 AK024160 AK293072 BAF85761 AK308127 BC040506 AAH40506 BC065374 BX647597 XM_005259794 XP_005259851 XM_005259795 XP_005259852 XM_005259797 XP_005259854 XM_006722673 XP_006722736 XM_011527749 XP_011526051 XM_011527750 XP_011526052 XM_011527751 XP_011526053 XM_011527752 XP_011526054 XM_011527753 XP_011526055 XM_011527754 XP_011526056 XM_011527755 XP_011526057 NM_133473 NP_597730 |
| Function | Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). {ECO:0000250}. |
| Subcellular Location | Nucleus {ECO:0000250}. |
Panoply™ Human ZNF431 Knockdown Stable Cell Line - CSC-DC018049 from Creative biogene
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