Gene Symbol | ZNF431 |
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Entrez Gene | 170959 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | zinc finger protein 431 |
Other Description | - |
Swissprots | Q8TF32 Q8IWC4 A8KAK7 |
Accessions | EAW84888 EAW84889 EAW84890 Q8TF32 AB075849 BAB85555 AK021615 AK024160 AK293072 BAF85761 AK308127 BC040506 AAH40506 BC065374 BX647597 XM_005259794 XP_005259851 XM_005259795 XP_005259852 XM_005259797 XP_005259854 XM_006722673 XP_006722736 XM_011527749 XP_011526051 XM_011527750 XP_011526052 XM_011527751 XP_011526053 XM_011527752 XP_011526054 XM_011527753 XP_011526055 XM_011527754 XP_011526056 XM_011527755 XP_011526057 NM_133473 NP_597730 |
Function | Sequence-specific DNA binding transcriptional repressor. Represses target gene transcription by recruiting HDAC1 and HDAC2 histone deacetylases. Acts as a specific transcriptional repressor for PTCH1 during embryonic development. Required for osteoblast differentiation and sonic hedgehog/SHH signaling response. Binds to the consensus site 5'-GCGCCC-3' in the promoter of PTCH1 (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. |
ZNF431 CRISPR/Cas9 KO Plasmid (h) - sc-418437 from Santa Cruz Biotechnology
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ZNF431 HDR Plasmid (h) - sc-418437-HDR from Santa Cruz Biotechnology
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ZNF431 Double Nickase Plasmid (h) - sc-418437-NIC from Santa Cruz Biotechnology
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ZNF431 Double Nickase Plasmid (h2) - sc-418437-NIC-2 from Santa Cruz Biotechnology
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ZNF431 CRISPR Activation Plasmid (h) - sc-418437-ACT from Santa Cruz Biotechnology
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ZNF431 CRISPR Activation Plasmid (h2) - sc-418437-ACT-2 from Santa Cruz Biotechnology
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ZNF431 Lentiviral Activation Particles (h) - sc-418437-LAC from Santa Cruz Biotechnology
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ZNF431 Lentiviral Activation Particles (h2) - sc-418437-LAC-2 from Santa Cruz Biotechnology
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ZNF431 siRNA (h) - sc-97851 from Santa Cruz Biotechnology
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ZNF431 shRNA Plasmid (h) - sc-97851-SH from Santa Cruz Biotechnology
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ZNF431 shRNA (h) Lentiviral Particles - sc-97851-V from Santa Cruz Biotechnology
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ZNF431 RNAi - H00170959-R01 from Novus Biologicals
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CompoZr® Knockout ZFN Kit - CKOZFN23450 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND23450 from Sigma-Aldrich
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ZNF431 siRNA (Human) - CRJ6131 from Cohesion Biosciences
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ZNF431 - MBS8226807 from MyBioSource
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shRNA set against Human ZNF431 (NM_133473.2) - SHH453928 from Creative biogene
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Human ZNF431 siRNA - orb276632 from Biorbyt
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ZNF431 shRNA Plasmid (Human) - CHJ6131 from Cohesion Biosciences
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ZNF431 miRNA 3'UTR clone - MiUTR3H-16800 from Creative biogene
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