Gene Symbol |
MARC2
|
Entrez Gene |
54996
|
Alt Symbol |
MOSC2
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
mitochondrial amidoxime reducing component 2
|
Other Description |
MOCO sulphurase C-terminal domain containing 2|MOSC domain-containing protein 2, mitochondrial|moco sulfurase C-terminal domain-containing protein 2|molybdenum cofactor sulfurase C-terminal domain-containing protein 2
|
Swissprots |
Q5VXC7 B2D0R5 Q969Z3 Q7L317 Q9NWU0 Q5VT67 D3DTB3 Q0JSK7 Q9H066
|
Accessions |
ACB21048 CAC51155 EAW93292 EAW93293 EAW93294 EAW93295 Q969Z3 AK000583 AK000612 BAA91287 AL136931 CAB66865 AM393019 CAL37897 AM393631 CAL38507 BC010366 BC011973 AAH11973 BC015829 AAH15829 BC016859 AAH16859 XM_005273168 XP_005273225 XM_006711407 XP_006711470 XM_011509683 XP_011507985 XM_011509684 XP_011507986 XR_247029 NM_017898 NP_060368
|
Function |
As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. {ECO:0000269|PubMed:21029045}.
|
Subcellular Location |
Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome {ECO:0000250}.
|