Gene Symbol | MARC2 |
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Entrez Gene | 54996 |
Alt Symbol | MOSC2 |
Species | Human |
Gene Type | protein-coding |
Description | mitochondrial amidoxime reducing component 2 |
Other Description | MOCO sulphurase C-terminal domain containing 2|MOSC domain-containing protein 2, mitochondrial|moco sulfurase C-terminal domain-containing protein 2|molybdenum cofactor sulfurase C-terminal domain-containing protein 2 |
Swissprots | Q5VXC7 B2D0R5 Q969Z3 Q7L317 Q9NWU0 Q5VT67 D3DTB3 Q0JSK7 Q9H066 |
Accessions | ACB21048 CAC51155 EAW93292 EAW93293 EAW93294 EAW93295 Q969Z3 AK000583 AK000612 BAA91287 AL136931 CAB66865 AM393019 CAL37897 AM393631 CAL38507 BC010366 BC011973 AAH11973 BC015829 AAH15829 BC016859 AAH16859 XM_005273168 XP_005273225 XM_006711407 XP_006711470 XM_011509683 XP_011507985 XM_011509684 XP_011507986 XR_247029 NM_017898 NP_060368 |
Function | As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively. {ECO:0000269|PubMed:21029045}. |
Subcellular Location | Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome {ECO:0000250}. |
MOSC2 CRISPR/Cas9 KO Plasmid (h) - sc-409982 from Santa Cruz Biotechnology
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MOSC2 HDR Plasmid (h) - sc-409982-HDR from Santa Cruz Biotechnology
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MOSC2 Double Nickase Plasmid (h) - sc-409982-NIC from Santa Cruz Biotechnology
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MOSC2 Double Nickase Plasmid (h2) - sc-409982-NIC-2 from Santa Cruz Biotechnology
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MOSC2 CRISPR Activation Plasmid (h) - sc-409982-ACT from Santa Cruz Biotechnology
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MOSC2 CRISPR Activation Plasmid (h2) - sc-409982-ACT-2 from Santa Cruz Biotechnology
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MOSC2 Lentiviral Activation Particles (h) - sc-409982-LAC from Santa Cruz Biotechnology
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MOSC2 Lentiviral Activation Particles (h2) - sc-409982-LAC-2 from Santa Cruz Biotechnology
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MOSC2 siRNA (h) - sc-88738 from Santa Cruz Biotechnology
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MOSC2 shRNA Plasmid (h) - sc-88738-SH from Santa Cruz Biotechnology
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MOSC2 shRNA (h) Lentiviral Particles - sc-88738-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU074191 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN14483 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14483 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03522 from Sigma-Aldrich
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MARC2 siRNA (Human) - CRJ0391 from Cohesion Biosciences
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shRNA set against Human MOSC2 (NM_017898.3) - SHH343668 from Creative biogene
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shRNA set against Human MOSC2(NM_017898.3) - SHH196265 from Creative biogene
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Human MARC2 siRNA - orb270892 from Biorbyt
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MARC2 shRNA Plasmid (Human) - CHJ0391 from Cohesion Biosciences
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MARC2 miRNA 3'UTR clone - MiUTR1H-06387 from Creative biogene
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