FOXN1

Gene Symbol FOXN1
Entrez Gene 8456
Alt Symbol FKHL20, RONU, WHN
Species Human
Gene Type protein-coding
Description forkhead box N1
Other Description Rowett nude|forkhead box protein N1|winged helix nude|winged-helix nude|winged-helix transcription factor nude
Swissprots B2R9Q7 O15353 O15352
Accessions CAA72417 EAW51092 O15353 AF086453 AK313878 BAG36604 BC140423 AAI40424 BC146539 AAI46540 Y11739 CAA72416 XM_005258046 XP_005258103 XM_011525354 XP_011523656 XM_011525355 XP_011523657 XM_011525356 XP_011523658 XM_011525357 XP_011523659 XM_011525358 XP_011523660 XM_011525359 XP_011523661 XM_011525360 XP_011523662 XM_011525361 XP_011523663 XM_011525362 XP_011523664 XM_011525363 XP_011523665 XM_011525364 XP_011523666 XM_011525365 XP_011523667 XM_011525366 XP_011523668 XM_011525367 XP_011523669 XM_011525368 XP_011523670 XM_011525369 XP_011523671 XM_011525370 XP_011523672 NM_003593 NP_003584
Function Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, including MHC Class II, DLL4, CCL25, CTSL, CD40 and PAX1. Regulates the differentiation of the immature TECs into functional cortical TECs (cTECs) and medullary TECs (mTECs). Essential for maintenance of mTECs population in the postnatal thymus. Involved in the morphogenesis and maintenance of the three-dimensional thymic microstructure which is necessary for a fully functional thymus. Plays an important role in the maintenance of hemato
Subcellular Location Nucleus.
Tissue Specificity Expressed in thymus.

FOXN1 (E-3) - sc-271256 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FOXN1 (E-3): sc-271256. Western blot analysis of FOXN1 expression in Raji whole cell lysate (A) and SK-MEL-28 nuclear extract (B).

FOXN1 (G-20) - sc-23566 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FOXN1 (G-20): sc-23566. Western blot analysis of FOXN1 expression in non-transfected: sc-117752 (A) and human FOXN1 transfected: sc-128644 (B) 293T whole cell lysates.

FOXN1 (H-270) - sc-30195 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FOXN1 (H-270): sc-30195. Western blot analysis of FOXN1 expression in SK-MEL-28 nuclear extract (A) and U-87 MG (B), C6 (C), T98G (D) and MTE1D (E) whole cell lysates.

FOXN1 (N-15) - sc-26330 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

FOXN1 (P-16) - sc-26331 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
FOXN1 (P-16): sc-26331. Immunoperoxidase staining of formalin fixed, paraffin-embedded human tonsil tissue showing nuclear staining of cells in germinal centers and cells in non-germinal centers.

Anti-FOXN1 antibody - ab192319 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FOXN1 antibody (ab192319)Lane 1 : HeLa whole cell lysateLane 2 : NIH 3T3 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-FOXN1 antibody - ab170793 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Flow cytometric analysis of A549 cells using ab170793 at a 1/10 dilution  (right/green histogram) compared to a negative control cell (left/blue histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used.

Anti-FOXN1 antibody - ab113235 from Abcam

Prices $407.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
ab113235 at 10ug/ml staining FOXN1 in Formalin-fixed, Paraffin-embedded Human Uterus tissue by Immunohistochemistry.

Anti-FOXN1 antibody - ab26069 from Abcam

Prices $370.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Ab26069 (20ug/ml) staining human FOXN1 in human thymus medulla tissue by immunohistochemistry using paraffin embedded tissue. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. In paraffin embedded Human Thymus Medulla shows speculate nuclear staining in some of the Medullar cells.

Anti-FOXN1 antibody - ab115222 from Abcam

Prices $407.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Human thymus, Medulla (formalin fixed, paraffin embedded) stained with ab115222 at 20 ug/ml followed by biotinylated anti Goat IgG secondary antibody, alkaline phosphatase streptavidin and chromogen.

Anti-FOXN1 antibody - ab96374 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-FOXN1 antibody (ab96374) at 1/1000 dilution + Raji whole cell lysate at 30 µg

Anti-FOXN1 Antibody (aa635-648) IHC-plus™ - LS-B10 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-FOXN1 antibody IHC of human thymus, medulla. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10 concentration 20 ug/ml.

Anti-FOXN1 Antibody IHC-plus™ - LS-B4832 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-FOXN1 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4832 concentration 10 ug/ml.

Anti-FOXN1 Antibody (aa450-500) - LS-C190813 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa350-378, APC) - LS-C235388 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa51-100) - LS-C31360 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: Raji Cell Lysate

Anti-FOXN1 Antibody (aa350-378, Biotin) - LS-C235387 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa350-378, AP) - LS-C235385 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa350-378, FITC) - LS-C235389 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa357-386) - LS-C321445 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody - LS-C340898 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody (aa350-378, Azide-free, HRP) - LS-C249009 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-FOXN1 Antibody - LS-C47358 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of FOXN1 in mouse thymus lysate. Lane 1 shows pre-immune sera. Lane 2 shows antibody tested at 1:5000 on mouse thymus lysate.

Anti-FOXN1 Antibody (aa350-378) - LS-C166234 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
FOXN1 Antibody western blot of A549,NCI-H460 cell line lysates (35 ug/lane). The FOXN1 antibody detected the FOXN1 protein (arrow).

Anti-FOXN1 Antibody (aa350-378, PE) - LS-C235392 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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