Gene Symbol |
Abhd12
|
Entrez Gene |
76192
|
Alt Symbol |
1500011G07Rik, 6330583M11Rik, AI431047, AW547313
|
Species |
Mouse
|
Gene Type |
protein-coding
|
Description |
abhydrolase domain containing 12
|
Other Description |
2-arachidonoylglycerol hydrolase|abhydrolase domain-containing protein 12|monoacylglycerol lipase ABHD12
|
Swissprots |
A2ANB4 Q99M06 Q99LR1
|
Accessions |
EDL28584 EDL28585 EDL28586 Q99LR1 AK018261 AK160126 AK177491 AK178029 AK178560 AK178612 AK183821 AK185693 AK192948 AK194284 AK195364 AK198485 AK200651 AK202769 AK206881 AK208808 AK211159 AK214944 AK215521 AK216141 AK217770 AK219355 AK219995 BC002138 AAH02138 BC002263 AAH02263 XM_006500365 XP_006500428 XM_006500366 XP_006500429 XM_006500367 XP_006500430 NM_024465 NP_077785
|
Function |
Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (PubMed:23297193). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways (PubMed:18096503). {ECO:0000269|PubMed:18096503, ECO:0000269|PubMed:23297193}.
|
Subcellular Location |
Membrane {ECO:0000269|PubMed:18096503}; Single-pass membrane protein {ECO:0000269|PubMed:18096503}. Mitochondrion {ECO:0000269|PubMed:20657592}.
|