Gene Symbol | Abhd12 |
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Entrez Gene | 76192 |
Alt Symbol | 1500011G07Rik, 6330583M11Rik, AI431047, AW547313 |
Species | Mouse |
Gene Type | protein-coding |
Description | abhydrolase domain containing 12 |
Other Description | 2-arachidonoylglycerol hydrolase|abhydrolase domain-containing protein 12|monoacylglycerol lipase ABHD12 |
Swissprots | A2ANB4 Q99M06 Q99LR1 |
Accessions | EDL28584 EDL28585 EDL28586 Q99LR1 AK018261 AK160126 AK177491 AK178029 AK178560 AK178612 AK183821 AK185693 AK192948 AK194284 AK195364 AK198485 AK200651 AK202769 AK206881 AK208808 AK211159 AK214944 AK215521 AK216141 AK217770 AK219355 AK219995 BC002138 AAH02138 BC002263 AAH02263 XM_006500365 XP_006500428 XM_006500366 XP_006500429 XM_006500367 XP_006500430 NM_024465 NP_077785 |
Function | Lysophosphatidylserine (LPS) lipase that plays a key role in the central nervous system. Represents a major LPS lipase in the brain (PubMed:23297193). May also have a 2- arachidonoylglycerol (2-AG) hydrolase activity and act as a regulator of endocannabinoid signaling pathways (PubMed:18096503). {ECO:0000269|PubMed:18096503, ECO:0000269|PubMed:23297193}. |
Subcellular Location | Membrane {ECO:0000269|PubMed:18096503}; Single-pass membrane protein {ECO:0000269|PubMed:18096503}. Mitochondrion {ECO:0000269|PubMed:20657592}. |
ABHD12 CRISPR/Cas9 KO Plasmid (m) - sc-429273 from Santa Cruz Biotechnology
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ABHD12 HDR Plasmid (m) - sc-429273-HDR from Santa Cruz Biotechnology
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ABHD12 Double Nickase Plasmid (m) - sc-429273-NIC from Santa Cruz Biotechnology
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ABHD12 Double Nickase Plasmid (m2) - sc-429273-NIC-2 from Santa Cruz Biotechnology
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ABHD12 CRISPR Activation Plasmid (m) - sc-429273-ACT from Santa Cruz Biotechnology
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ABHD12 CRISPR Activation Plasmid (m2) - sc-429273-ACT-2 from Santa Cruz Biotechnology
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ABHD12 Lentiviral Activation Particles (m) - sc-429273-LAC from Santa Cruz Biotechnology
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ABHD12 Lentiviral Activation Particles (m2) - sc-429273-LAC-2 from Santa Cruz Biotechnology
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ABHD12 siRNA (m) - sc-140766 from Santa Cruz Biotechnology
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ABHD12 shRNA Plasmid (m) - sc-140766-SH from Santa Cruz Biotechnology
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ABHD12 shRNA (m) Lentiviral Particles - sc-140766-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EMU151131 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN26072 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND26072 from Sigma-Aldrich
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ABHD12 siRNA (Mouse) - CRM9594 from Cohesion Biosciences
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ABHD12 - MBS8202740 from MyBioSource
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shRNA set against Mouse ABHD12 (NM_024465.3) - SHH229414 from Creative biogene
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shRNA set against Mouse Abhd12(NM_024465.3) - SHG025669 from Creative biogene
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Mouse ABHD12 siRNA - orb289070 from Biorbyt
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ABHD12 shRNA Plasmid (Mouse) - CHM9594 from Cohesion Biosciences
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ABHD12 miRNA 3'UTR clone - MiUTR1M-01063 from Creative biogene
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