Gene Symbol |
CLIC6
|
Entrez Gene |
54102
|
Alt Symbol |
CLIC1L
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
chloride intracellular channel 6
|
Other Description |
chloride channel form A|chloride intracellular channel protein 6|parchorin
|
Swissprots |
Q8IX31 A8K0U8 Q96NY7
|
Accessions |
EAX09775 EAX09776 Q96NY7 AF308293 AF426169 AAL24813 AF448438 AAN76729 AF448439 AAN76730 AK092733 BAC03959 AK289663 BAF82352 BC040196 AAH40196 BC169220 XM_011529650 XP_011527952 NM_053277 NP_444507
|
Function |
May insert into membranes and form chloride ion channels. May play a critical role in water-secreting cells, possibly through the regulation of chloride ion transport (By similarity). {ECO:0000250}.
|
Subcellular Location |
Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Predominantly cytoplasmic. Upon chloride ion efflux from the cell, it is translocated to the plasma membrane (By similarity). {ECO:0000250}.
|
Tissue Specificity |
Expressed in brain, placenta, pancreas and liver. {ECO:0000269|PubMed:12226712}.
|